We included in a controlled study 38 consecutive patients aged up to 75 with newly diagnosed cancer of the prostate suitable for hormonal treatment (stage C-D). Patients were randomized to receive either flutamide and orchidectomy or flutamide alone. After 4 years the survival rate for the orchidectomy plus flutamide group (53%) appears to be better than for the group with flutamide alone (40%).
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2.
CrawfordE.D., BlumensteinB.A., GoodmanP.J., DavisM.A., EisenbergerM.A., McLeodD.G., SpauldingJ.T., BensonR., DorrF.A.: Leuprolide with and without flutamide in advanced prostatic cancer. Cancer, 66: 1039, 1990.
3.
IversenP., SuciuS., SylvesterR., ChristensenI., DenisL.: Zoladex and flutamide versus orchiectomy in the treatment of advanced prostatic cancer: a combined analysis of two European studies, EORTC 30853 and DAPROCA 86Cancer, 66: 1067, 1990.
