We report our experience in the treatment of renal staghorn stones. 74 patients were treated with PCNL followed, when necessary, by one or more ESWL treatments for residual fragments, achieving a stone-free status in 64/74 patients (86.5%). Treatment with ESWL monotherapy (6 cases) resulted in a stone-free status in 3 patients (50%). According to our experience, PCNL followed by ESWL, is the most adequate treatment for staghorn kidney stones. We reserve PCNL with multiple percutaneous access and ESWL monotherapy for selected patients.
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