Failure of Neutrophils to Recover Their Ability to Produce Superoxide after Stunning by a Conventional,Acidic,Lactate-Based Peritoneal Dialysis Solution
Restricted accessResearch articleFirst published online April, 1994
Failure of Neutrophils to Recover Their Ability to Produce Superoxide after Stunning by a Conventional,Acidic,Lactate-Based Peritoneal Dialysis Solution
Exposure of human neutrophils to conventional, acidic, lactate-based peritoneal dialysis solutions for 5 minutes results in a depression of superoxide generation. In spite of restoration of extracellular pH to 7.4, these stunned cells failed to recover their ability to generate the anion after a period of an hour.
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