In comparison with healthy persons, chronic uremic patients on regular hemodialysis treatment had significantly higher blood serum concentrations of α1-acid glycoprotein, ceruloplasmin and C4 complement component, while levels of haptoglobin, C3 and transferrin were lower. Serum α2-macroglobulin and α1-antitrypsin levels were similar in both groups. Hemodialysis with cuprophan membrane induced only slight changes in some of these glycoproteins during a 48-hour follow-up period. Seven hours after termination of hemodialysis slight, but significant, decreases in blood serum transferrin and α1-antitrypsin concentrations were observed. Hemodialysis thus does not seem to induce a conspicuous acute-phase reaction.
TettaC, JeantetA, CamussiG, Direct interaction between polymorphonuclear neutrophils and cuprophan membranes in a plasma-free model of dialysis. Proc Eur Dial Transplant Ass1984; 21:150–5.
LuciakM, TchórzewskiH, TrznadelK.Release of neutrophil granule factors during early period of hemodialysis: a possible cause of hemodialysis neutropenia. Nephron1984; 37:30–4.
5.
MahioutA, JörresA, HissR, MeinholdH, KesselM.Effects of blood-dialyser interaction on prostaglandins in uremic patients and in healthy man. Nephrol Dial Transplant1987; 2:546–50.
DocciD, TurciF.Serum alpha-1-acid glycoprotein levels in uremic patients on hemodialysis. Nephron1983; 33:72.
16.
HenriksenHJO, PetersenMU, PedersenFB. Serum alpha-1-acid glycoprotein (orosomucoid) in uremic patients on hemodialysis. Nephron1982; 31:24–6.
17.
AronsenKF, EklundG, KindmarkCO, LaurellCB. Sequential changes of the plasma proteins after surgical trauma. Scand J Clin Lab Invest1972; 29 (suppl. 124): 127–36.
18.
CrocksonRA, PayneCJ, RatcliffAP, SoothillJF. Time sequence of acute phase reactive proteins following surgical trauma. Clin Chim Acta1966; 14:435–41.
19.
WaldA, WolfowitzJ.On a test whether two samples are from the same population. Ann Math Stat1940; 11:147–62.
20.
WilcoxonF.Individual comparisons by ranking methods. Biometrics Bull1945; 1: 80–83.
21.
LernerR, WernerB, AsabaHFernstedtB, ElmquistE.Assessment of hemolysis in regular hemodialysis patients by measuring carbon monoxide production rate. Clin Nephrol1983; 20:239–43.
22.
ChenowethDE, CheungAK, HendersonLW. Anaphylatoxin formation during hemodialysis: effects of different dialyzer membranes. Kidney Int1983; 24:764–9.
23.
SchmickerR, TessenowW.Serumtransferrin bei chronischer Niereninsuffizienz unter konservativer Therapie und Hämodialyse. Ztschr Urol Nephrol1978; 71:13–20.
24.
MarečkovaO, MarečekZ, VulterinovaM, The effect of a low-protein diet on serum levels of ceruloplasmin and transferrin in patients with chronic renal failure. Clin Nephrol1978; 9:38–40.
25.
ChenTSN, LeevyCM. Liver regeneration and uraemia. Brit J Exp Pathol1973; 54:591–6.
26.
GrossmanSB, ShafritzDA. Influence of chronic renal failure on protein synthesis and albumin metabolism in rat liver. J Clin Invest1977; 59:869–78.
27.
BergströmJ, AlvestrandA, GutierrezA.Acute and chronic metabolic effects of hemodialysis. In: SmebyLC, JørstadS, WiderøeTE, eds. Immune and metabolic aspects of therapeutic blood purification systems.Basel: Karger, 1986; 254–73.
28.
TravisJ, SalvesenGS. Human plasma proteinase inhibitors. Ann Rev Biochem1983; 52:655–709.
29.
GoiG, FabiA, LombardoA, Circadian and circannual rhythms of several enzymes of lysosomal origin in human plasma. Clin Chim Acta1988; 176:1–8.
