Shifts in the visible spectrum of aqueous bilirubin (BR) resulting from the addition of soluble polyvinylpyrrolidone (PVP) suggest specific interactions. Hence, isotherms were determined for the adsorption of BR from aqueous solution onto solid, cross-linked PVP and onto cholestyramine (CA) (used as a reference adsorbent) at 0, 10, 20 and 25°C. Although adsorption onto PVP reaches equilibrium values more rapidly than for CA, the latter adsorbent has a larger capacity. Furthermore the isotherms for PVP are independent of temperature while those for CA show an increase in BR adsorbed with an increase in temperature.
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MøllerJ.: Agar Ingestion and Serum Bilirubin Values in Newborn Infants.Acta Obstet. Ginec. Scand.53, 61, 1974.
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NicolopoulosD., HadjigeorgiouE., MalamitsiA., KalpoyannisN., KarliI., PapadakisD.: Combined Treatment of Neonatal Jaundice with Cholestyramine and Phototherapy.The J. of Pediatrics.93, 684, 1978.
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OlssonL., SamuelsonO.: Chromatography of Aromatic Acids and Aldehydes and Phenols on Cross-Linked Polyvinylpyrrolidone.J. of Chromatography.93, 189, 1974.
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PloussardJ.P., FoliotA., StofovB., PetiteJ.P., AlisonF., EtienneJ.P., HoussetE.: Intérêt et Limite de I'Utilisation d'un Capteur Intestinal de la Bilirubine Non-Conjuguée (polyvinylpyrrolidone) dans I'lctère du Prématuré.Arch. Franc. Péd.29, 373, 1972.
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PollandR.L., OdellG.B.: Physiologic Jaundice, The Enterohepatic Circulation of Bilirubin.The New England J. of Medicine.284, 1, 1972.
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RomagnoliC., PolidoniG., FoschiniM., Cataldi, De TurnsP., TortoroloG., MastrangeloR.: Agar in the Management of Hyperbilirubinemia in the Premature Baby.Archives of Disease in Childhood.50, 202, 1975.
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ScharschmidtB.P., PlotzP.H., BerkP.D., WagonnerJ.G., VergallaJ.: Removing Substances from Blood by Affinity Chromatography II: Removing Bilirubin from the Blood of Jaundiced Rats by <Hemoperfusion over Albumin-Conjugated Agarose Beads.J. Clin. Inv.53, 786, 1974.
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TonH.Y., HughesR.D., SilkD.B.A., WilliamsR.: Albumin Coated Amberlite XAD-7 Resin for Hemoperfusion in Acute Liver Failure Part I, Adsorption Studies.Art. Org.3, 20, 1979.
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UlstromR.A., EisenklanE.: The Enterohepatic Shunting of Bilirubin in the Newborn Infant.The J. of Pediatrics.62, 27, 1964.
