It is our intention to present a short review of various approaches to the non-conventional treatment of hepatic failures of the fulminant type. Our review is directed to the scientist, technologist, and clinician with a budding interest in the hepatic assist area. We shall discuss parabiosis, liver transplants, and various extracorporeal devices including hemoperfusion, hemodialysis, and enzymic detoxification systems.
We feel that the present technological approaches to the treatment of hepatic failure are very primitive at this stage. Some of the recent advances are very encouraging, and it is our opinion that these approaches show great promise in the long term.
PopperHans, and PaulD.Berk, Chairman's Summary, NIH On Fulminant Hepatic Failure, Bethesda, MD., February 1977.
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Hepatic Assist has been expanded as a topic recently in the NIH Conference on Fulminant Hepatic Failure in Bethesda, and the Second International Symposium for Artificial Organs in Tokyo. Interest has visibly increased in recent meetings of the American Society for Artificial Internal Organs and various engineering society conferences. In addition, two new journals have begun publication within the last year or so: «Artificial Organs» sponsored by the International Society for Artificial Organs, and this journal, «The International Journal of Artificial Organs», which is in fact divided into eight independent sections, at least four of which may include hepatic assist information.
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