Abstract
[Purpose]
Bi-Digital O-Ring Test, originally founded and developed by Omura Y. in New York (1977-2004; as following BDORT), is used for cancer treatments in our Clinic. Regarding the treatment of breast cancer patients, the metastasis nests of a patient post-operative of breast cancer with the whole body metastasis and skin metastasis were spontaneously disappeared by following the guidance of BDORT. So the similar prescription was instructed to other patients of breast cancer and as a result some patients have shown remarkable clinical progress. So 4 cases were reported here.
[Materials & Methods]
The prescription for the patients of breast cancer is basically Barley Green® (Barley Powder)3P3×, Cilantro Tablet® 6T3×, Ipe Roxo (Taheebo Tea), Tsumura Jyuzen-Taiho-To (TJ48) 7.5g3× and Anastrozole (Arimidex® , hormone medicine) 1mg Tablet l×. Lactobacillus Product (ORT-Ecocci®) was prescribed, if there is a necessity. Patients were followed up by BDORT diagnosis, Chest X-ray inspection, CT(Computed Tomography) inspection and tumor markers, etc.
[Case Reports]
Case No.1
54 years old woman. Post-operative of breast metastasis in the whole body Tsumura Jyuzen-Taiho-To (TJ48) 7.5g3×, Barley Green® 3P3×, Ipe Roxo, EPA-α® 3P3×, Cilantro® 6T3× and Anastrozole 1T1× were prescribed. After 2 months later, the doses of EPA-α® and Cilantro® were increased to 2 capsules or tablets at one prescription time. As shown in Fig. 1 the tumor markers were decreased remarkably.

Change of Cancer Parameters
Case No.2
64 years old woman. Postoperative of breast cancer, metastasis in the whole body Tsumura Jyuzen- Taiho-To (TJ48) 7.5g3×, Barley Green® 3P3×, Ipe Roxo, EPA-α3P3×, Epadel® 2P2×, Cilantro® 6T3× and Anastrozole 1T1× were prescribed. As shown in Fig.2, Fig.3, Integrin α5β1 was markedly deceased and Acetylcholine was increased normal body. Finally her whole body metastasis and skin metastasis were disappeared.

Change of the Parameters
Case No.3
47 years old woman. Post-operative of breast cancer, bone metastasis. Tsumura Jyuzen-Taiho-To (TJ48) 7.5g3×, Epadel® 2P2×, Barley Green® 3P3×, Cilantro® 6T3× and Ipe Roxo were prescribed. Her immunocompetence was low (IL-12; 20pg, IFN-γ; 10 pg). As shown in Fig. 4, the levels of CEA and CA15-3 were decreased and she was in an improvement trend. By the abdomen ultrasonography inspection in February, the shadows in the liver were sized Φ10 mm large and Φ13 mm large. The shadow was reduced in size to Φ8 mm large in April.

Change of the Parameters
Case No.4
74 years old woman. Post-operative of breast cancer, strongly suspicious of lung metastasis and liver metastasis. In September 2003, lung metastasis and liver metastasis were strongly suspected with the results of chest X-ray and also abdomen CT inspection. So, ORT-Ecocci® 9T3×, Ipe Roxo, Cilantro Tablet® 6T3×, Tsumura Jyuzen-Taiho-To (TJ48) 3P3×, Barley Green® 3P3×, Anastrozole 1T1× and Epadel® 2P2× were prescribed. Her immunocompetence was checked by BDORT (IL-12;2ng, IFN-γ;2ng).

Change of the Parameters
Three months later, suspected shadows of lung and liver metastasis were disappeared on the chest X-rayphotograph and abdomen CT photograph in Fig.6. Her immunocompetence was progressed in good condition (IL-12;20ng, IFN-γ;22ng).
Discussion
The introduced prescription in this report was seemed to be effective in the treatment for the patients of breast cancer. The combination of this prescriptions seemed that elevate the immunity ability of IL-12 and IFN-γ and decrease the level of the inhibiting factors of immunocompetence as IL-10. So the synergistic effects raise the activity of Natural Killer Cells. The combination of prescriptions were seemed to be effective in totally. In some cases the levels of tumor markers were decreased in a few months. Further examination is necessary in this study, and also trials in the same protocol in other hospitals should be necessary.
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