Quick and Non-invasive Screening & Diagnosis of Cancer by Measuring Telomere,8-OH-dG Integrin α5β1,Acetylcholine,Hg etc. and Safe & Effective Treatment of Cancer: Marked Decrease of the Telomere of Cancer Cell & Increase of the Normal Cell Telomere by Stimulating the Press Needle Inserted at True St .36 and Effective Treatment & Longevity Effect of Selective Drug Uptake Enhancement Method.

Abstract

Our research on cancer tissue indicates that the following abnormal parameters coexist: 1) marked increase in Oncogene C-fos Ab2; 2) marked increase in Integrin α5β1; 3) marked increase in Hg; 4) marked decrease in Acetylcholine; 5) marked increase in viral infection; 6) marked decrease in NO (change is similar and proportional to the change in Acetylcholine); 7) increase in Glucose (maximum about 2 times the blood glucose level); 8) increase in Telomere (amount of increase in cancer cell Telomere is about 5 to 10 times the normal cell of the same organ); 9) increase in Cycline E; 10) increase in KI 67; 11) increase in 8-OH-dG (8-hydroxy- 2’-deoxyGuanosine); and 12) marked decrease in Folic Acid. Since 1990; for non-invasive screening of cancer, the author used either 60ng of Oncogene C-fos Ab2 or 60ng of Integrin α5β1 as reference control substance for non-invasive quick laser beam screening of the cancer, the author only used 4 extremities, but since 2000, the following 6 locations are routinely used for the initial basic cancer screening which require 2-3 minutes: 1) right hand palm; 2) Suprasternal Notch corresponding to acupuncture point CV22, tian tu; 3) left hand palm; 4) Umbilicus; 5) right upper thigh; 6) left upper thigh. Red spectrum laser beam wife wavelength of 560-670nm with 1-5mW output is projected from the hand of the intermediary to these 6 locations one-by-one to find whether there is strong resonance or not. If CV22 is cancer positive, to rule out cancer in the brain, R- & L-ear lobules should also be examined. If the umbilicus or upper thigh is cancer positive, anus, the back of the upper thigh, and vertebrae L1 & L5 areas will be examined by projecting laser beam. If any area shows a cancer-positive response using the same or similar red spectrum laser line, the whole body is scanned using X-Axis Laser Line Scanning and Y-Axis Laser Line Scanning, and a red line is drawn on the positive area. The crossing points of the X-axis and Y-axis Integrin α5β1 strong positive area is often the center of the cancer positive area. Once the center of the cancer positive areas are localized, the actual boundary of each cancer is mapped using a metal electrode by detecting resonance using 60ng Integrin α5β1. Once the exact location & outline of fee cancer is identified, the cell type of each cancer can be identified non-invasively using microscope slide of different cancers, and then laboratory confirmation for sensitive cancer markers for specific cancer will be ordered along with standard imaging studies using most suitable method among X-ray, CT Scan, MRI, PET Scan or Ultrasonic imaging techniques. For cancer markers, the author made a convenient chart of a list of about 45 sensitive cancer markers for different kinds of cancers. Since 2003 the author checks the Telomere at first. Instead of 60ng Integrin α5β1, we use 110ng Telomere (TTAGGG) with red spectrum laser pointer. If normal cell Telomere is lower than 110ng, presence of cancer should be suspected and the amount of 8-OH-dG (a marker of DNA mutation) should be checked. According to our experience, if 8-OH-dG is more than 70ng, cancer is suspected. Then X-, Y-axis laser scanning method with 60ng Integrin α5β1 is performed. Also we measure the level of Folic acid. Role of Folic acid is to prevent the DNA mutation. Therefore cancer treatment is not sufficient without sufficient Folic Acid in the patients’ body. Our recent study on the substances known to increase longevity revealed mixture of about 100-75 mg of Acetyl-L-Camitine and about 50 mg of Lipoic Acid also was found to reduce cancer Telomere and increase normal cell Telomere. Further study indicated that addition of 100-75 mg of Acetyl-L-Camitine (which is known to enhance mitchondorial lipid metabolism) to our EPA 180mg + DHA 120mg, 100mg of Cilantro Tablet + 100μg of Folic Acid also significantly enhance anti-cancer effect. Once cancer is identified, either standard cancer therapy (such as surgery, chemotherapy, radiation therapy) or the following more safe & natural alternative methods of treatment, or a modified standard treatment combined with our safe alternative method, are used after the patient obtains a 2nd or 3rd opinion and discusses treatment with their regular physician. Regardless of the treatment method, if any medication is used, the degree of potential beneficial effects of each medication as well as compatibility, drug ineffectiveness or toxicity, and drug interactions with other medications can be detected using the Bi-Digital O-Ring Test before giving multiple medications to a specific cancer patient. The author found that many patients are taking many substances well known to be effective for cancer but, often, no anti-cancer effect exists due to the canceling effect of drug interactions among multiple effective medications, and the cancer spreads more quickly than if the patient were taking just one effective anti-cancer drug.

If the number of the tumors is few and the location of the tumor is clearly identifiable, the Selective Drug Uptake Enhancement Method (which was originally discovered by this author in 1990 after successfully mapping the accurate organ representation areas on the hands and other different parts of the body) is used to deliver effective medication selectively to the pathological area while markedly reducing drug uptake to normal parts of the body by stimulating accurate organ representation areas on the hands or other parts of the body, including feet and ears. However, when there are multiple metastases and the number of the cancer positive areas are more than 15 or 20, the Selective Drug Uptake Enhancement Method requires more than full-time attention because each organ representation area requires 15-30 minutes stimulation every 4-6 hours to maintain drug uptake. Our non-toxic, safe, natural approach to cancer treatment uses, for the average adult, a gelatin capsule of 180 mg EPA with 120 mg DHA as a safe and effective anti-viral agent, and 100 mg of Cilantro compound, the effect of which was discovered in 1995 by the author, to remove localized excessive deposits of Hg in cancer cells as well as other abnormally deposited metals such as Al and Pb in non-cancerous tissue. If the drug uptake is maintained continuously and effectively, often the cancer shrinks. As a result, one can co-exist with cancer by making cancer inactive, but often with this method cancer cells are not completely destroyed. When the Selective Drug Uptake Enhancement Method is used in the presence of 2 or 3 cancer positive areas, it is possible to manage by spending 15-30 min. stimulating the organ representation areas corresponding to each cancer positive area after taking medication for cancer treatment. In the presence of multiple cancer metastases (more than 15-20 metastases), it is not possible to stimulate each one of the organ representation areas.

However, in 1998, the author succeeded in lowering die cancer telomere while increasing the normal cell telomere. The cancer cell telomere can be decreased very significantly and the normal cell telomere can be increased by giving acupuncture at True St.36, which is located next to the Tibial Tuberosity, and it usually has a round shape with a diameter 8-12mm, depending on the individual. The Traditional SL36 is located on the extension of the same Tibial Tuberosity, laterally beyond the location of the True St.36. However, since 1984, using the Bi-Digital O-Ring Test Resonance Phenomena between 2 identical substances, it became possible to localize the exact location of an acupuncture point and the 12 major meridians. According to this study, in the location described in Traditional St.36, there is no acupuncture point. The medial boundary of True St.36 is touching the Anterior Tibial Crest at the borderline of the Tibial Tuberosity of the same leg. In some individuals there are 2 (or even 3) Tibial Tuberosities on the same tibial bone, but usually the one nearest (or 2nd nearest) to the knee is the correct one. The exact location and outline of True St.36 can be accurately localized using a microscope slide of stomach tissue by detecting the boundary between strong resonance and no resonance. Since 2000, the author has refined the technique by semi-permanently inserting a tiny press needle (about 2 mm in length) attached to a small band-aid that is precut in a round or rectangular shape. When the press needle that is inserted on True St.36 was stimulated by the thumb or index finger, the author succeeded in lowering die cancer cell telomere of 1,000 - 1,400 ng to less than 1yg (10^-24 g). Since the average lowest amount of telomere found in living humans according to our study is 100ng, with rare exceptions, when the telomere becomes much less than 100ng, cancer cell may not be able to divide, and under certain conditions may end up apoptotic. Therefore, die lowering of the telomere to less than lyg most likely inhibits cell division of the cancer cell. Our study indicates that as long as one can maintain stimulation of True SL 36, after taking mixture of EPA 180mg & DHA 120mg, special 100mg Cilantro tablet and folic acid 100-150μg 4 times each day, abnormal cancer cell parameters can be reduced close to 0 (cancer cell activity is practically inhibited) in an average adult In addition, the author also found that not only does abnormally increased cancer cell telomere (1100-1600ng) goes down dose to 0 (1 yg=10^-24g), but also all of the anti-cancer medication selectively enters all the metastatic cancer tissue while drug uptake to normal tissue markedly diminishes. As a result, this method becomes a highly efficient treatment for improving or prolonging the life of the terminal cancer patient with multiple metastasis.

In 2000, the author stimulated a small press needle semi-permanently inserted at True St.36 for 15-20 minutes as often as he could everyday for more than a few weeks, and the cancer parameters were reduced to almost zero, but new skin cancer appeared in the elbow as the result of excessive increase of normal cell telomere of about 300ng to over 2000ng-2500ng and excessive exposure of skin to strong sunlight (The extremity was exposed to strong sun at Phoenix, AZ). To avoid excessive stimulation and maintain safety, we now limit the total amount of manual stimulation to anywhere between 150-200 times after taking each dose of medication, depending on the patient For cancer of the chest, neck, oral cavity, face, and head, stimulation of the press needle inserted on the True LI.4 of the hands can induce a similar effect as True St.36. However, it is more difficult to keep the press needle in True LI.4 for a long time, as the hand not only moves often but also is often wet when washing the hand or face, but it is possible to keep small press needle with a band-aid on True St.36 for 1 month or even longer. Stimulation of a semi-permanently inserted press needle at True St.36 or True LI.4 is often very effective for treatment of various bacterial or viral infections that cause intractable pain or muscle paralysis with administration of effective anti-viral or anti bacterial agents. In order to maintain effective drug uptake with the Selective Drug Uptake Enhancement Method, Bi-Digital O-Ring Test negative underwear contacting skin above the pathological area must be replaced by positive underwear, otherwise drug uptake will be markedly inhibited. Similarly, negative watches, metal necklaces, metal bracelets, metal earrings, credit cards, etc., should not be worn close to the skin of the cancer patient.

In addition, the author has been evaluating the reason why cancer is almost non-existent in the heart and small intestine. To explain this, the author proposed the hypothesis that these organs may be secreting anti-cancer substances, particularly the small intestine (jejunum and ileum). This idea was first evaluated by the author himself as the cancer subject. Stimulation of the accurate organ representation areas of the small intestine on both hands each time markedly reduced all the cancer parameters. If this hypothesis is correct, then there is a possibility that stimulation of the accurate organ representation area of the small intestine may reduce existing cancer parameters of cancerous tissue in any organ. Therefore, the technique was repeated with other cancer patients, and a similar result was obtained. While repeating this study with the author himself, it was found that occasionally stimulation of the small intestine representation areas of both hands could not produce maximum reduction of cancer parameters. However, additional stimulation of the accurate organ representation area of the gall bladder on the hand produced significant reduction of cancer parameters. When both the accurate small intestine representation area and the gall bladder representation area are stimulated at the same time, reduction of cancer parameters toward normal was maximum. Usually stimulation of the small intestine representation area on the side ipsilateral to the cancer-positive area produced the strongest cancer parameter-reducing effect. In addition, stimulation of the organ representation area on the hands (or feet, tongue or ears) corresponding to the cancer-positive area enhanced drug uptake to the cancer tissue very significantly, as an application of the Selective Drug Uptake Enhancement Method. These findings may have very important clinical implications. Also the nature & role of Integrin α5β1 rich blood vessels supplying blood for the growth of cancer as well as factors inhibiting blood vessel growth to the cancer tissue are being evaluated.

When cancer cell telomere was reduced below 1 yg, normal cell telomere increased significantly, and anti-cancer drug uptake at all the cancer tissue, including their metastasis, was selectively enhanced (Selective Drug Uptake Enhancement Method), while drug uptake to normal tissue reduces markedly. When acupuncture was given on traditional St. 36, no significant changes were observed in both cancer cell and normal cell Telomere. In order to maintain these beneficial effects of True St. 36, a small thumbtack-like indwelling needle was inserted at True St. 36 and held by a round band-aid. EPA & DHA in a gelatin capsule as a safe, natural anti-viral agents, and Cilantro to remove excessive Hg deposit from cancer cells were given 4 times daily. Patients were instructed to apply mechanical stimulation on the indwelling micro needle at True St.36 after taking the medication.

Thus, acupuncture on Trite St. 36 is potentially highly beneficial as a clinically important supplement to the treatment of cancer, particularly with terminal cancer with multiple metastasis. Since he also mapped recently more accurate organ representation area of the hand and according to this new organ representation area of die hand, small intestine occupies much broader area above large intestine representation area. While mapping this, the author noticed that gall bladder representation area is very sensitive in both hands, particularly in the left hand. Further indicated that lower half of the gall bladder is mainly controlled by organ representation area in the left hand and upper half of the gall bladder in mainly represented by the right hand representation area. Because of this, the author stimulated the new accurate representation are of the colon the part above which represented the small intestine, was also accidentally stimulated. Because the author had a very busy schedule, he forgot to take Cilantro as an anti-cancer medication, but he noticed that cancer marker did not increase. As a consequence he speculated that gall bladder may be secreting some anti-cancer substance, and this should be further investigated since small intestine is known that it is the only organ of the GI system that does not develop cancer. After stimulation of gall bladder with just two times of EPA/DHA and Cilantro, the gall bladder returned to almost normal except Acetylcholine remained very low, and Hg and Integrin and Oncogene reduced to less than 10ng and remain low in spite of not taking anti-cancer medication.

Telomere at the center of the cancer as well as surrounding normal tissues will be measured using different amount of one of the basic units of human Telomere, TTAGGG Our safe cancer treatment frequently consists of 1) Cilantro to remove excessive Hg from cancer cell, 2) mixture of EPA/DHA as antiviral agent, 3) Folic acid to reduce DNA mutation & 4) Acetyl-L-Camitine with Selective Drug Uptake Enhancement Method with or without press needle at True St. 36 to deliver medication specifically to cancer positive area (with or without standard treatment). Therefore, a similar method was repeated with terminal cancer patients with adenocarcinoma of the lung, small cell carcinoma of lung, as well as patients with adenocarcinoma of the colon, prostate cancer, breast cancer, uterine cancer and anaplastic astrocytoma of brain. While giving mixture of EPA and DHA and Cilantro most of the patients’ cancer telomere went down below 1 yg from anywhere between 1000ng to 1400 ng and all the above described cancer parameters improved very significantly with reduction in the tumor size and improvement of symptoms.