We have measured levels of contaminants (products of cell lysis and other substances) in blood salvaged from patients undergoing primary cemented total hip replacement. Washing of this blood removed an average of 91.4% of the free haemoglobin mass, reduced white cell lysozyme concentrations by 86% and almost totally eliminated fats and particulate matter. Osmotic fragility was significantly improved by washing although not to control levels.
Haemolysis and renal dysfunction associated with autotransfusion [Hazard]. Health Devices1990; 19: 25–27.
2.
OrrM., BlenkoJ.The use of washed red cells as an adjunct to component therapy. Surgery1978; 84: 728–730.
3.
Automated intraoperative processing autotransfusion machines. Health Devices1988; 17: 219–242.
4.
McKenneyJ., ValeriC.R., MohandasN., FortierN., GiorgioA., SnyderL.M.Decreased in vivo survival of hydrogen peroxide-damaged baboon red blood cells. Blood1990; 76: 206–211.
5.
SchaffH.V., HauerJ.M., BellW.R.Autotransfusion of shed mediastinal blood after cardiac surgery. A prospective study. J Thorac Cardiovasc Surg1978; 75: 632–641.
6.
RonaiA.K., GlassJ.J., ShapiroA.S.Improving autologous blood harvest: Recovery of red cells from sponges and suction. Anaesth Intens Care1987; 15: 421–424.
7.
GoldfingerD.Acute haemolytic transfusion reactions — a fresh look at pathogenesis and considerations regarding therapy. Transfusion1977; 17: 85.
8.
SchmidtP.J., HollandP.V.Pathogenesis of the Acute Renal Failure associated with incompatible transfusion. Lancet1967; ii: 1169.
9.
MalikS., BalkwillF.R.Tumour Necrosis Factor. Br Med J1988; 296: 1214.
10.
TateR.M., RepineJ.E.Neutrophils and the Adult Respiratory Distress syndrome. Am Rev Resp Dis1983; 128: 552–559.
11.
JacksonJ.H., CochraneC.G.Leucocyte-induced tissue injury. Haematol/Oncol Clin North Am1988; 2(2): 317–334.
12.
Editorial.Neutrophils and Adult Respiratory Distress syndrome. Lancet1984; ii: 790–791.
13.
DorangL.A., KlebanoffG., KemmererW.T.Autotransfusion in long-segment spinal fusion. An experimental model to demonstrate the efficacy of salvaging blood contaminated with bone fragments and marrow. Am J Surg1972; 123: 686–688.
