Intravenous infusions of nitroglycerin decreased systemic systolic, pulmonary systolic and wedge pressures in β-blocked patients anaesthetised for coronary artery surgery with high dose of fentanyl without changing heart rate, diastolic pressure, or cardiac index, thus leading to an improvement in endocardial viability ratio.
The use of a nitroglycerin bolus to abort an acute myocardial ischaemic episode is described.
StengertK.B., WilseyB.L., HurleyE.J., GrehlT.M., LurieA.J., KleinR.C., UpjohnL.R.Incremental intravenous nitroglycerin for control of afterload during anaesthesia in patients undergoing myocardial revascularisation. Anaesthetist1978; 27: 223–227.
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FrankeN., SchmuckerP., van AckernK., KreuzerE., ReichartB.Antihypertensive Therapie mit Nitroglycerin wahrend der Narkose bei koronarchirurgischen Eingriffen. Anaesthetist1979; 28: 484–488.
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HempelmanG., PiepenbrookS., SeitzW., KarlikzekG.Changes in haemodynamic parameters, inotropic state, and myocardial oxygen consumption with intravenous nitroglycerin. J Thorac Cardiovasc Surg1977; 73: 836–847.
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ChestnutJ.S., AlbinM.S., Gonzales-AbolaE., NewfieldP., MaroonJ.C.Clinical evaluation of nitroglycerin for neurosurgery. J Neurosurg1978; 48: 704–711.
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