The effects of liquid heparin on the analysis of acid/base status of arterial blood include a reduction in Pco2and an increase in Po2. A study was performed to compare a lyophilised heparin syringe with a liquid heparin glass syringe for collection of blood for acid/base analysis. No significant difference between the variables measured in blood taken in the two syringes was demonstrated.
Siggard AndersonO.Sampling and storing of blood for determination of acid-base status. Scand J Clin Lab Invest1961; 13: 196–204.
2.
BradleyJ.G.Errors in the measurement of blood Pco2 due to dilution of the sample with heparin solution. Br J Anaesth1972; 44: 231–234.
3.
HansenJ.E., SimmonsD.H.A systematic error in the determination of blood PCO2. Am Rev Resp Dis1977; 115: 1061–1063.
4.
HamiltonR.D., CrockettA.J., AlpersJ.H.Arterial blood gas analysis: potential errors due to the addition of heparin. Anaesth Intens Care1978; 6: 251–255.
5.
SheffeH.A.The analysis of variance.Wiley, New York, 1959.