Propofol is widely used for sedation in critically ill patients. Several adult patients, all with acute neurological disorders, have been reported suffering from propofol infusion syndrome, which occurs in patients receiving high-dose propofol and catecholamines and/or steroids. We present a case of a septic patient without neurological illness who developed propofol infusion syndrome.
KangT.M.Propofol infusion syndrome in critically ill patients.Ann Pharmacother2002; 36: 1453–1456.
2.
VasileB., RasuloF., CandianiA., LatronicoN.The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome.Intensive Care Med2003; 29: 1417–1425.
3.
CremerO.L., MoonsK.G., BoumanE.A., KruijswijkJ.E., de SmetA.M., KalkmanC.J.Long-term propofol infusion and cardiac failure in adult head-injured patients.Lancet2001; 357: 117–118.
4.
SchenkmanK.A., YanS.Propofol impairment of mitochondrial respiration in isolated perfused guinea pig hearts determined by reflectance spectroscopy.Crit Care Med2000; 28: 172–177.
