Advanced Colorectal Cancer Meta-analysis Project: Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate.J Clin Oncol, 10: 896–903, 1992.
2.
Advanced Colorectal Cancer Meta-analysis Project: Meta-analysis of randomized trials testing the biochemical modulation of fluorouracil by methotrexate in metastatic colorectal cancer.J Clin Oncol, 10: 960–969, 1994.
3.
Meta-analysis Group in Cancer: Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer.J Clin Oncol, 16: 301–308, 1998.
4.
HaskellC.M., SelchM.T., RammingK.P.: Colon and rectum. In: HaskelCM (Ed): Colon and rectum in cancer treatment (III ed), pp. 232–254, Saunders, Philadelphia, PA, 1990.
5.
CreemersG.J., LundB., VerwejJ.: Topoisomerase I inhibitors: topotecan and irinotecan.Cancer Treat. Rev., 20: 73–96, 1994.
6.
ChenA.Y., LiuL.F.: DNA topoisomerases: essential enzymes and lethal targets.Annu Rev Pharmacol Toxicol, 34: 191–218, 1994.
7.
GiovanellaB.C., StehlinJ.S., WallM.E.: DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts.Science, 246: 1046–1048, 1989.
8.
ShimadaP., RothenbergM., HilsenbeckS.G.: Activity of CPT-11 (irinotecan hydrochloride), a topoisomerase I inhibitor against human colony-forming units.Anticancer Drugs, 5: 20–26, 1994.
9.
ChenA.Y., YuC., PotmesilM.: Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells.Cancer Res, 51: 6039–6044, 1991.
10.
WaniM.C., RonmanP.E., LindleyJ.T., WallM.E.: Plant antitumor agents.18. Synthesis and biological activity of camptothecin analogues. J Med Chem, 23: 554–560, 1980.
11.
SugimotoY., TsukaharaS., Oh-HaraT.: Decreased expression of DNA topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody.Cancer Res, 50: 6925–6930, 1990.
12.
TamuraH., KohchiC., YamadaR.: Molecular cloning of a cDNA topoisomerase I and identification of mutation sites.Nucleic Acids Res, 51: 1129–1136, 1991.
13.
RothenbergM.L., KuhnJ.G., BurrisH.A.III: Phase I and pharmacokinetic trial of weekly CPT-11.J Clin Oncol, 11: 2194–2204, 1993.
14.
De ForniM., BugatR., ChabotG.G.: Phase I and pharmacokinetic study of the camptothecin derivative irinotecan, administered on a weekly schedule in cancer patients.Cancer Res, 54: 4347–4354, 1994.
15.
RowinskyE.K., GrochowL.B., EttingerD.S.: Phase I and pharmacological study of the novel topoisomerase I inhibitor 7-ethyl-10-[4-(1 -piperidino)-1 -piperidino]-carbonyloxy-camptothecin (CPT-11) administered as a ninety-minute infusion every 3 weeks.Cancer Res, 54: 427–436, 1994.
16.
AbigergesD., ChabotG.G., ArmandJ.P.: Phase I and pharmacokinetic studies of the camptothecin analog irinotecan administered every 3 weeks in cancer patients.J Clin Oncol, 13: 210–221, 1995.
17.
CatimelG., ChabotG.G., GuastallaJ.P.: Phase I and pharmacokinetic study of irinotecan (CPT-11) administered daily for three consecutive days every three weeks in patients with advanced solid tumors.Ann Oncol, 6: 133–140, 1995.
18.
GandiaD., AbigergesD., ArmandJ.P.: CPT-11-induced cholinergic effects in cancer patients.J Clin Oncol, 11: 196–197, 1993 (letter).
19.
ChabotG.G., AbigergesD., CatimelG.: Population pharmacokinetics and pharmacodynamics of irinotecan (CPT-11) and active metabolite SN-38 during phase I trials.Ann Oncol, 6: 141–151, 1995.
20.
KanedaN., NagataH., FurutaT., YokokuraT.: Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse.Cancer Res, 50: 1715–1720, 1990.
21.
ShimadaY., YoshimoM., WakuiA.: Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer.J Clin Oncol, 11: 909–913, 1993.
22.
RothenbergM.L., EckardtJ.E., KuhnJ.G.: Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer.J Clin Oncol, 14: 1128–1135, 1996.
23.
PitotH.C., WenderD.B., O'ConnellM.J.: Phase II trial of irinotecan in patients with metastatic colorectal carcinoma.J Clin Oncol, 15: 2910–2919, 1997.
24.
MasudaS., FukuokaM., KusunokiY.: A new derivative of camptothecin for the treatment of refractory or relapsed small-cell lung cancer.J Clin Oncol, 10: 1225–1229, 1992.
25.
Von HoffD.D., RothenbergM.L., PitotH.C.: Irinotecan (CPT-11) therapy for patients with previously treated metastatic colorectal cancer (CRC): overall results of FDA-reviewed pilotai US clinical trials.J Clin Oncol, 16: 228a, 1997 (abs 803).
26.
RougierP., BugatR., DouillardJ.Y.: Phase II study of irinotecan in the treatment of advanced colorectal cancer in che motherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy.J Clin Oncol, 15: 251–260, 1997.
27.
Van CutsemE., RougierP., DrozJ.P.: Clinical benefit of irinotecan (CPT-11) in metastatic colorectal cancer (CRC) resistant to 5-FU.J Clin Oncol, 16: 268a, 1997 (abs 950).
28.
CunninghamD., PyrrhönenS., JamesR.D.: Randomized trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer.Lancet, 352: 1413–1418, 1998.
29.
RougierP., Van CutsemE., BajettaE.: Randomized trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer.Lancet, 352: 1407–1412, 1998.
30.
ContiJ.A., KemenyN.E., SaltzL.B.: Irinotecan is an active agent in untreated patients with metastatic colorectal cancer.J Clin Oncol, 14: 709–715, 1996.
31.
PozzoC., PyrhönenS., BodrogiI.: A randomized phase II trial assessing irinotecan (IRI) and 5FU/folinic acid (LV), “Mayo regimen”, in first line palliative chemotherapy patients with metastatic colorectal cancer.Proc. ECCO 10, Eur J Cancer, 35: S71 (abstr 213), 1999.
32.
Van CutsemE., PozzoC., StarkhammarH.: A phase II study of irinotecan alternated with five days bolus of 5-fluorouracil and leucovorin in first-line chemotherapy of metastatic colorectal cancer.Ann Oncol, 9: 1199–1204, 1998.
33.
SaltzL.B., LockerP.K., PirottaN.: Weekly irinotecan (CPT-11), leucovorin (LV), and fluorouracil (FU) is superior to daily × 5 LV/FU in patients with previously untreated metastatic colorectal cancer.Proc. ASCO, 18: 233a (abstr 898), 1999.
34.
DouillardJ.Y., CunninghamD., RothA.D.: A randomized phase III trial comparing irinotecan (IRI) + 5FU/folinic acid (FA) to the same schedule of 5FU/FA in patients with metastatic colorectal cancer as front line chemotherapy.Proc. ASCO, 18: 233a (abstr 899), 1999.