Chronic lymphedema predisposes for local Immune incompetence, manifested by development of Stuart-Treves syndrome, Kaposi's sarcoma and fibroma-like lesions. A 91-year-old female with multiple cancers developed classic Kaposi's sarcoma on a chronically lymphedematous arm 26 years after radical mastectomy and irradiation of the involved axilla. The Kaposi lesion partially responded to electron beam irradiation.
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References
1.
CaputoR., GianottiR., GrimaltR., MontiM., AlessiE.: Soft fibroma-like lesions on the legs of a patient with Kaposi's sarcoma and lymphedema.Am. J. Dermathopathol., 13: 493–496, 1991.
2.
KutenA., SapirD., CohenY.: Postirradiation soft tissue sarcoma occurring in breast cancer patients: report of seven cases and results of combination chemotherapy.J. Surg. Oncol., 28: 168–171, 1985.
3.
RuoccoV., AstaritaC., GuerreraV., Lo SchiavoA., MoscarielloC.G., SatrianoR.A., PisaniM.: Kaposi's sarcoma on a lymphedematous immunocompromised limb.Int. J. Dermatol., 23: 56–60, 1984.
4.
StarkR.B., DwyerE.M., De ForestM.: Effect of surgical ablation of regional lymph nodes on survival of skin homo-grafts.Ann. NY. Acad. Sci., 87: 140–146, 1960.
5.
StewartF.W., TrevesN.P.: Lymphangiosarcoma in post-mastectomy lymphedema: A report of six cases with elephantiasis chirurgica.Cancer, 1: 64–81, 1948.
