Abstract
Rabbits’ immune sera treated with endocellular fractions of sarcoma Galliera, isolated by fractioned centrifugation, were studied « in vivo » and « in vitro » in relation to their action on the tumour. Rabbit's sera immunized with nuclei and with the supernatant of sarcoma Galliera did not inhibit « in vivo » the development of the already established tumour in rats as well as the tumour implanted into the rat following the introduction of a dose of serum. On the other hand, rabbits’ sera immunized with mitochondria of sarcoma Galliera showed an «in vivo» toxic action on the already established sarcoma, leading to its complete regression. A dose of immune serum failed to prevent the « taking » of the tumour subsequently implanted into the rat. Rabbit serum immunized with mitochondria of sarcoma Galliera showed an « in vitro » toxic action on the mitochondria of the tumour itself.
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