We describe a rare case of extranodal marginal zone/low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) combined with areas of well-differentiated adenocarcinoma. In addition, the MALT lymphoma was synchronously systemic, with involvement of the lung, stomach and duodenum.
ChanA.O., ChuK.M., YuenS.T., LeungS.Y., LamS.K., WongJ.: Synchronous gastric adenocarcinoma and mucosa associated lymphoid tissue lymphoma in association with Helicobacter pylori infection: comparing reported cases between the East and West. Am J Gastroenterol, 96: 1922–1924, 2001.
2.
IchiharaE., TabataM., TakigawaN., SatoY., KondoE., AoeM., KiuraK., TanimotoM.: Synchronous pulmonary MALT lymphoma and pulmonary adenocarcinoma after metachronous gastric MALT lymphoma and gastric adenocarcinoma. J Thorac Oncol, 3: 1362–1363, 2008.
ThieblemontC., BergerF., DumontetC., MoulletI., BouafiaF., FelmanP., SallesG., CoiffierB.: Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed. Blood, 95: 802–806, 2000.
5.
KossM.N.: Malignant and benign lymphoid lesions of the lung. Ann Diagn Pathol, 8: 167–187, 2004.
6.
ChilosiM., ZinzaniP.L., PolettiV.: Lymphoproliferative lung disorders. Sem Resp Crit Care Med, 26: 490–501, 2005.
7.
TakeshimaF., KunisakiM., AritomiT., OsabeM., AkamaF., NakasoneT., NiinoD., KatayamaS., IsomotoH., OmagariK., MizutaY., MurataI., KohnoS.: Hepatic mucosa-associated lymphoid tissue lymphoma and hepatocellular carcinoma in a patient with hepatitis B virus infection. J Clin Gastroenterol, 38: 823–826, 2004.
8.
NakamuraS., AoyagiK., IwanagaS., YaoT., TsuneyoshiM., FujishimaM.: Synchronous and metachronous primary gastric lymphoma and adenocarcinoma. A clinicopathological study of 12 patients. Cancer, 79: 1077–1085, 1997.
9.
GrinsteinS., PreciadoM.V., GattusoP., ChabayP.A., WarrenW.H., De MatteoE., GouldV.E.: Demonstration of Epstein-Barr virus in carcinomas of various sites. Cancer Res, 62: 4876–4878, 2002.
10.
MorbiniP., RiboniR., TomaselliS., RossiA., MagriniU.: Eber-and LMP-1-expressing pulmonary lymphoepithelioma-like carcinoma in a Caucasian patient. Hum Pathol, 34: 623–625, 2003.
11.
ConwayE.J., HudnallS.D., LazaridesA., BahlerA., FraireA.E., CagleP.T.: Absence of evidence for an etiologic role for Epstein-Barr virus in neoplasms of the lung and pleura. Mod Pathol, 9: 491–495, 1996.
12.
RichmondI., PritchardG.E., AshcoftT., AveryA., CorrisP.A., WaltersE.H.: Bronchus associated lymphoid tissue (BALT) in human lung: its distribution in smokers and non-smokers. Thorax, 48: 1130–1134, 1993.
13.
NicholsenA.G., WotherspoonA.C., JonesA.L., SheppardM.N., IsaacsonP.G., CorrinB.: Pulmonary B-cell non-Hodgkin's lymphoma associated with autoimmune disorders: a clinicopathological review of six cases. Eur Respir J, 9: 2022–2025, 1996.
14.
StagnaroE., TuminoR., ParodiS., CrosignaniP., FontanaA., MasalaG., MiligiL., NanniO., RamazzottiV., RodellaS., Senoiri ConstantiniA., ViganoC., VindigniC., VineisP.: Non-Hodgkin's lymphoma and type of tobacco smoke. Cancer Epidemiol Biomarkers Prev, 13: 431–437, 2004.