Abstract
The use of MR imaging has been proposed for the assessment of the hepatic iron overload in transfusion-dependent thalassemic patients treated with desferrioxamine. The aim of the study was to correlate serum ferritine levels and MR signal intensity of the liver parenchyma. Results on 12 patients showed that the ratios between the signal intensity of liver parenchyma and muscle and fat are promising parameters for predicting iron overload.
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References
1.
Brasch
R. C.
Wesbey
G. E.
Gooding
C. A.
Koerper
M. A.
: Magnetic resonance imaging of transfusional hemosiderosis complicating thalassemia major . Radiology
150 (1984 ), 767 .
2.
Ehman
R. L.
Kjos
B. O.
Hricak
H.
Brasch
R. C.
Higgins
C. B.
: Relative intensity of abdominal organs in MR images . J. Comput. Assist. Tomogr.
9 (1985 ), 315 .
3.
Gomori
J. M.
Grossman
R. I.
Drott
H. R.
: MR relaxation times and iron content of thalassemic spleens . An in vitro study. AJR
150 (1988 ), 567 .
4.
Hernandez
J. R.
Sarnaik
S. A.
Lande
I.
: MR evaluation of liver iron overload . J. Comput. Assist. Tomogr.
12 (1988 ), 91 .
5.
Runge
V. M.
Clanton
J. A.
Smith
F. W.
: Nuclear magnetic resonance of iron and copper disease states . AJR
141 (1983 ), 943 .
6.
Stark
D. D.
: Liver . In : Magnetic resonance imaging , p. 934 . Edited by
Stark
D. D.
Bradley
W. G.
Jr.
C. V. Mosby Co. , St. Louis
1988 .
7.
Stark
D. D.
Moseley
M. E.
Bacon
B. R.
: Magnetic resonance imaging and spectroscopy of hepatic iron overload . Radiology
154 (1985 ), 137 .
