Hepatic angiography was performed in a double-blind two-group study in 60 patients using iohexol 350 mg I/ml and ***metrizoate 350 mg I/ml. A slight increase in serum values of hepatic enzymes was found when metrizoate was used, particularly in patients with impaired liver function. Iohexol gave considerably less pain and sensation of heat than did metrizoate. A non-expected significant increase of creatine kinase was recorded when iohexol was used. The reason for this is not yet known.
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4.
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MåreK.AlménT.: Liver toxicity of diatrizoate and a non-ionic contrast medium (C29). Coeliac angiography in the rabbit. Acta Radiol. Diagnosis21 (1980), 685.
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NilssonP. E.JonssonK.: Effect of ioxaglate on the liver and pancreas following selective angiography in man. Acta Radiol. Diagnosis25 (1984), 395.
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NymanU.AlménT.LandtmanM.: Effect of contrast media on femoral blood flow. Comparison between ionic monomelic, monoacidic dimeric and non-ionic contrast media in the dog. Acta radiol. (1980) Suppl. No. 362, p. 43.
9.
SalvesenS.: Local toxicity of metrizamide on intra-vascular injection. Effect on kidney, liver and blood-brain barrier. Acta radiol. (1977) Suppl. No. 335, p. 166.
10.
Acute intravenous toxicity of iohexol in the mouse and in the rat. Acta radiol. (1980) Suppl. No. 362, p. 73.
11.
SkalpeI. O.EvensenA.StrömmeJ. H.: Toxicity of metrizamide and metrizoate in selective coeliac angiography. An experimental investigation in rabbits. Acta radiol. (1973) Suppl. No. 335, p. 186.
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SkjennaldA.HeldaasJ.HøisethA.: Comparison of iohexol and meglumine-Na-Ca metrizoate in visceral angiography. Acta radiol. (1983) Suppl. No. 366, p. 158.
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TörnquistC.AlménT.GolmanK.HoltåsS.: Proteinuria following nephroangiography. VII. Comparison between ionic monomelic, monoacidic dimeric and non-ionic contrast media in the dog. Acta radiol. (1980) Suppl. No. 362, p. 49.
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TrägårdhB.: Coronary angiography with iohexol and other contrast media in the dog. II. Left ventricular contractility and work. Acta radiol. (1980) Suppl. No. 362, p. 21.
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TrägårdhB.CederlundC.-G.: Coronary angiography with iohexol and other contrast media in the dog. III. Contractility of the left ventricle. Acta radiol. (1980) Suppl. No. 362, p. 25.
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