Rhythmic auditory stimulation for reduction of falls in Parkinson’s disease: a randomized controlled study

Abstract

Objective:

To test whether rhythmic auditory stimulation (RAS) training reduces the number of falls in Parkinson’s disease patients with a history of frequent falls.

Design:

Randomized withdrawal study design.

Subjects:

A total of 60 participants (aged 62–82 years) diagnosed with idiopathic Parkinson’s disease (Hoehn and Yahr stages III or IV) with at least two falls in the past 12 months.

Intervention:

Participants were randomly allocated to two groups and completed 30 minutes of daily home-based gait training with metronome click–embedded music. The experimental group completed 24 weeks of RAS training, whereas the control group discontinued RAS training between weeks 8 and 16.

Main measures:

Changes in clinical and kinematic parameters were assessed at baseline, weeks 8, 16, and 24.

Results:

Both groups improved significantly at week 8. At week 16—after the control group had discontinued training—significant differences between groups emerged including a rise in the fall index for the control group (M = 10, SD = 6). Resumption of training reduced the number of falls so that group differences were no longer significant at week 24 (M_experimental = 3, SD = 2.6; M_control = 5, SD = 4.4; P > 0.05). Bilateral ankle dorsiflexion was significantly correlated with changes in gait, fear of falling, and the fall index, indicating ankle flexion as a potential kinematic mechanism RAS addresses to reduce falls.

Conclusion:

RAS training significantly reduced the number of falls in Parkinson’s disease and modified key gait parameters, such as velocity and stride length.