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Abstract

Objectives

The aim is to evaluate venous stent patency, the development of post-thrombotic syndrome, recurrence, quality of life and the optimal post-procedural anticoagulation regimen in the treatment of iliofemoral deep venous thrombosis.

Method and results

EMBASE and Medline databases were interrogated to identify studies in which acute deep venous thrombosis patients were stented. Twenty-seven studies and 542 patients were identified. Primary, assisted primary and secondary patency rates 12 months after stent placement ranged from 74 to 95, 90 to 95 and 84 to 100%, respectively. The observed post-thrombotic syndrome rate was 14.6%. The incidence of stent re-thrombosis was 8%. In 26% of studies, patients received additional antiplatelet therapy. Quality of life questionnaires employed in 11% of studies, demonstrating an improvement in the chronic venous insufficiency questionnaire (22.67 ± 3.01 versus 39.34 ± 6.66).

Conclusion

Venous stenting appears to be an effective adjunct to early thrombus removal; however, further studies are needed to identify optimal anticoagulant regimen and effect on quality of life.

Keywords

Stent venous thromboembolism acute endovascular treatment May–Thurner syndrome

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References

White

. The epidemiology of venous thromboembolic disease venous thromboembolism. Circulation 2003; 107: 14–8.

Neglen

Raju

Iliocaval obstruction: endovascular treatment. In: Cronenwett

Wayne Johnston

(eds). Rutherford's vascular surgery, Philadelphia, PA: Saunders, an imprint of Elsevier Inc., 2014, pp. 955–970.

Enden

Haig

Kløw

et al.

Long-term outcome after additional catheter-directed thrombolysis versus standard treatment for acute iliofemoral deep vein thrombosis (the CaVenT study): a randomised controlled trial. Lancet 2012; 379: 31–38.

Kahn

. The post-thrombotic syndrome: progress and pitfalls. Br J Haematol 2006; 134: 357–365.

Meissner

Gloviczki

Comerota

et al.

Early thrombus removal strategies for acute deep venous thrombosis: clinical practice guidelines of the society for vascular surgery and the American Venous Forum. J Vasc Surg 2012; 55: 1449–1462.

Kahn

Hirsch

Shrier

et al.

Effect of postthrombotic syndrome on health-related quality of life after deep venous thrombosis. Arch Intern Med 2002; 162: 1144.

Bergqvist

Jendteg

Johansen

et al.

Cost of long-term complications of deep venous thrombosis of the lower extremities: an analysis of a defined patient population in Sweden. Ann Intern Med 1997; 126: 454.

Jenkins

. Endovascular therapies to treat iliofemoral deep venous thrombosis. Prog Cardiovasc Dis 2011; 54: 70–76.

Nazarian

Austin

Wegryn

et al.

Venous recanalization by metallic stents after failure of balloon angioplasty or surgery: four-year experience. Cardiovasc Intervent Radiol 1996; 19: 227–33.

10.

Kearon

Akl

Ornelas

et al.

Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report. Chest 2016; 149: 315–352.

11.

NICE | The National Institute for Health and Care Excellence, http://www.nice.org.uk/aboutnice/howwework/developingniceclini-calguidelines/clinicalguidelinedevelopmentmethods/theguidelinesmanual2007/the_guidelines_manual_2007.jsp (accessed 16 November 2016).

12.

Konstantinides

Torbicki

Agnelli

et al.

2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism. Eur Heart J 2014; 35: 3033–3080.

13.

Eijgenraam

ten Cate

ten Cate-Hoek

. Venous stenting after deep venous thrombosis and antithrombotic therapy: a systematic review. Rev Vasc Med 2014; 2: 88–97.

14.

Moher

Liberati

Tetzlaff

et al.

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 2009; 339: b2535. doi: 10.1136/bmj.b2535.

15.

Bækgaard

Just

. Indications for stenting during thrombolysis. Rev Vasc Med 2013; 1: 76–80.

16.

Alesh

Kayali

Stein

. Catheter-directed thrombolysis (intrathrombus injection) in treatment of deep venous thrombosis: a systematic review. Catheter Cardiovasc Interv 2007; 70: 143–148.

17.

Sharifi

Bay

Mehdipour

et al.

Thrombus Obliteration by Rapid Percutaneous Endovenous Intervention in Deep Venous Occlusion (TORPEDO) trial: midterm results. J Endovasc Ther 2012; 19: 273–280.

18.

Meng

Jiang

et al.

Stenting of iliac vein obstruction following catheter-directed thrombolysis in lower extremity deep vein thrombosis. Chin Med J 2013; 126: 3519–3522.

19.

Engelberger

Spirk

Willenberg

. Ultrasound-assisted versus conventional catheter-directed thrombolysis for acute iliofemoral deep vein thrombosis. J Vasc Surg 2015; 62: 518.

20.

Bækgaard

Broholm

Just

et al.

Long-term results using catheter-directed thrombolysis in 103 lower limbs with acute iliofemoral venous thrombosis. Eur J Vasc Endovasc Surg 2010; 39: 112–117.

21.

Fiengo

Bucci

Khalil

et al.

Original approach for thrombolytic therapy in patients with Ilio-femoral deep vein thrombosis: 2 years follow-up. Thromb J 2015; 13: 40.

22.

Srinivas

Patra

Reddy

et al.

Outcome of venous stenting following catheter directed thrombolysis for acute proximal lower limb venous thrombosis: a prospective study with venous Doppler follow-up at 1-year. Cardiovasc Interv Ther 2015; 30: 320–326.

23.

Patel

Stookey

Ketcham

et al.

Endovascular management of acute extensive iliofemoral deep venous thrombosis caused by. J Vasc Interv Radiol 2000; 11: 1297–1302.

24.

Manninen

Juutilainen

Kaukanen

et al.

Catheter-directed thrombolysis of proximal lower extremity deep vein thrombosis: a prospective trial with venographic and clinical follow-up. Eur J Radiol 2012; 81: 1197–1202.

25.

AbuRahma

Perkins

Wulu

et al.

Iliofemoral deep vein thrombosis: conventional therapy versus lysis and percutaneous transluminal angioplasty and stenting. Ann Surg 2001; 233: 752–760.

26.

Lamont

Pearl

Patetsios

et al.

Prospective evaluation of endoluminal venous stents in the treatment of the May-Thurner syndrome. Ann Vasc Surg 2002; 16: 61–64.

27.

Goldenberg

Branchford

Wang

et al.

Percutaneous mechanical and pharmacomechanical thrombolysis for occlusive deep vein thrombosis of the proximal limb in adolescent subjects: findings from an institution-based prospective inception cohort study of pediatric venous thromboembolism. J Vasc Interv Radiol 2011; 22: 121–132.

28.

Husmann

Heller

Kalka

et al.

Stenting of common iliac vein obstructions combined with regional thrombolysis and thrombectomy in acute deep vein thrombosis. Eur J Vasc Endovasc Surg 2007; 34: 87–91.

29.

Kim

J-Y

Choi

Guk Ko

et al.

Percutaneous treatment of deep vein thrombosis in May-Thurner syndrome. Cardiovasc Intervent Radiol 2006; 29: 571–575.

30.

Sillesen

Just

Jørgensen

et al.

Catheter directed thrombolysis for treatment of Ilio-femoral deep venous thrombosis is durable, preserves venous valve function and may prevent chronic venous insufficiency. Eur J Vasc Endovasc Surg 2005; 30: 556–562.

31.

Bloom

Farkas

Kalish

et al.

Pharmacomechanical catheter-directed thrombolysis for pregnancy-related iliofemoral deep vein thrombosis. J Vasc Interv Radiol 2014; 26: 992–1000.

32.

Hölper

Kotelis

Attigah

et al.

Longterm results after surgical thrombectomy and simultaneous stenting for symptomatic iliofemoral venous thrombosis. Eur J Vasc Endovasc Surg 2010; 39: 349–355.

33.

Kwak

H-S

Han

Y-M

Lee

Y-S

et al.

Stents in common iliac vein obstruction with acute ipsilateral deep venous thrombosis: early and late results. J Vasc Interv Radiol 2005; 16: 815–822.

34.

Avgerinos

Hager

Naddaf

et al.

Outcomes and predictors of failure of thrombolysis for iliofemoral deep venous thrombosis. J Vasc Surg Venous Lymphat Disord 2015; 3: 35–41.

35.

Hager

Yuo

Tahara

et al.

Outcomes of endovascular intervention for May-Thurner syndrome. J Vasc Surg Venous Lymphat Disord 2013; 1: 270–275.

36.

Herrera

Comerota

Thakur

et al.

Managing iliofemoral deep venous thrombosis of pregnancy with a strategy of thrombus removal is safe and avoids post-thrombotic morbidity. J Vasc Surg 2014; 59: 456–464.

37.

Xue

Huang

et al.

Catheter-directed thrombolysis and stenting in the treatment of iliac vein compression syndrome with acute iliofemoral deep vein thrombosis: outcome and follow-up. Ann Vasc Surg 2014; 28: 957–963.

38.

Lindow

Mumme

Asciutto

et al.

Long-term results after transfemoral venous thrombectomy for iliofemoral deep venous thrombosis. Eur J Vasc Endovasc Surg 2010; 40: 134–138.

39.

Stanley

Murphy

Plummer

et al.

Midterm results of percutaneous treatment for acute and chronic deep venous thrombosis. J Vasc Surg 2011; 54: 1851.

40.

Blättler

Heller

Largiadèr

et al.

Combined regional thrombolysis and surgical thrombectomy for treatment of iliofemoral vein thrombosis. J Vasc Surg 2004; 40: 620–625.

41.

Schünemann HJ, Oxman AD, Vist GE, et al. Chapter 12: interpreting results and drawing conclusions. In: Higgins JPT and Green S (eds) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 (updated March 2011). The Cochrane Collaboration, http://handbook.cochrane.org/chapter_12/12_8_chapter_information.htm (2011, accessed).

42.

Villalta

Bagatella

Piccioli

et al.

Assessment of validity and reproducibility of a clinical scale for the post-thrombotic syndrome (abstract). Haemostasis 1994; 24: 158a.

43.

Rutherford

Padberg

Comerota

et al.

Venous severity scoring: an adjunct to venous outcome assessment. J Vasc Surg 2000; 31: 1307–1312.

44.

Porter

Moneta

. Reporting standards in venous disease: an update. international consensus committee on chronic venous disease. J Vasc Surg 1995; 21: 635–645.

45.

Jayaraj

Meissner

. A comparison of villalta-prandoni scale and venous clinical severity score in the assessment of post thrombotic syndrome. Ann Vasc Surg 2014; 28: 313–317.

46.

Galanaud

Holcroft

Rodger

et al.

Comparison of the Villalta post-thrombotic syndrome score in the ipsilateral vs. Contralateral leg after a first unprovoked deep vein thrombosis. J Thromb Haemost 2012; 10: 1036–1042.

47.

Kahn

. Measurement properties of the Villalta scale to define and classify the severity of the post-thrombotic syndrome. J Thromb Haemost 2009; 7: 884–888.

48.

Launois

Reboul-Marty

Henry

. Construction and validation of a quality of life questionnaire in chronic lower limb venous insufficiency (CIVIQ). Qual Life Res 1996; 5: 539–54.

49.

Vedantham

Goldhaber

Kahn

et al.

Rationale and design of the ATTRACT Study: a multicenter randomized trial to evaluate pharmacomechanical catheter-directed thrombolysis for the prevention of postthrombotic syndrome in patients with proximal deep vein thrombosis. Am Heart J 2013; 165: 523–530.e3.

50.

Soosainathan

Moore

Gohel

et al.

Scoring systems for the post-thrombotic syndrome. J Vasc Surg 2013; 57: 254–261.

51.

Vedantham

Goldhaber

Julian

et al.

Pharmacomechanical catheter-directed thrombolysis for deep-vein thrombosis. N Engl J Med 2017; 377: 2240–2252.

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A systematic review on the use of deep venous stenting for acute venous thrombosis of the lower limb

Abstract

Objectives

Method and results

Conclusion

Keywords

Get full access to this article

References

Supplementary Material