Hereditary spherocytosis (HS) is a rare inherited haemolytic anaemia. This case report outlines a neonatal patient with presumed HS requiring cardiopulmonary bypass (CPB) and the whole blood exchange transfusion carried out in the immediate pre bypass setting to ensure a successful outcome.
Da CostaLGalimandJFenneteauO, et al.Hereditary spherocytosis, elliptocytosis, and other red cell membrane disorders. Blood Rev2013; 27(4): 167–178.
2.
Bolton-MaggsPHB. Hereditary spherocytosis; new guidelines. Arch Dis Child2004; 89: 809–812.
3.
PolletH. How cytoskeletal impairment in hereditary elliptocytosis and spherocytosis affects erythrocyte membrane composition, organization and deformation. PhD Thesis. Belgium: UCL-Université Catholique de Louvain, 2019.
4.
GallagherPGForgetBG. Hereditary spherocytosis, elliptocytosis and related disorders. Williams Hematology. 6th ed.New York, NY: McGraw-Hill, Health Professions Division, 2001, pp. 1189–1209.
AfrozaSAzizL. Anaesthetic management of a case of heriditary spherocytosis for splenectomy and cholecystectomy. J Bangladesh Soc Anaesthesiol2005; 18(1): 50–53.
7.
MamikonianLSMamoLBSmithPBKooJ, et al.Cardiopulmonary bypass is associated with hemolysis and acute kidney injury in neonates, infants, and children. Pediatr Crit Care Med2014; 15(3): e111–e119.
8.
MendralaKCzoberTDarochaT, et al.Hemolysis during open heart surgery in patients with hereditary spherocytosis — systematic review of the literature and case study. Perioper Med2024; 13: 54. DOI: 10.1186/s13741-024-00411-w.
9.
ChristensenRDYaishHMGallagherPG. A pediatrician’s practical guide to diagnosing and treating hereditary spherocytosis in neonates. Pediatrics2015; 135(6): 1107–1114. DOI: 10.1542/peds.2014-3516.
