Modified ultrafiltration warming technology in pediatric congenital heart disease surgery: A case‒control study

Abstract

Background

To evaluate the effect and safety of modified ultrafiltration warming technology during pediatric congenital heart disease (CHD) surgery.

Methods

A retrospective analysis included 68 children (<1 year) who underwent CHD correction surgery with cardiopulmonary bypass (CPB) and modified ultrafiltration (MUF). Patients were divided into a warmed MUF group (W-MUF, n = 38) and a conventional MUF group (n = 30). The W-MUF group used a dual-channel infusion warmer during MUF. Preoperative and postoperative parameters, including Nasopharyngeal temperature (NPT),rectal temperature (RT), hemoglobin (Hb), hematocrit (HCT),prothrombin time (PT), Prothrombin Time Ratio (PTR) ,pericardial drainage volume, the intensive care unit (ICU) stay, extubation time,and transfusion requirements were compared.

Results

No significant differences were found between groups preoperatively. The PT and prothrombin ratio in the MUF group were significantly prolonged compared to pre-MUF values and the W-MUF group (p < .05). After MUF, the W-MUF group had higher nasopharyngeal and rectal temperatures and shorter ICU stay, faster extubation time,and lower pericardial drainage volume compared to the MUF group (p < .05). The W-MUF group also required less fresh frozen plasma, cryoprecipitate,and platelets postoperatively (p < .05),while there was no significant difference in red blood cell (RBC) transfusion requirements between the two groups.

Conclusion

Modified ultrafiltration warming technology is safe and effective. It is beneficial for temperature regulation in CHD surgery and is worthy of promotion.

Keywords

modified ultrafiltration congenital heart disease cardiopulmonary bypass children hypocoagulable

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