Discoid lupus is an autosomal disease that has not been found to predispose to cancer. Pulmonary blastoma is a rare primary lung tumor with a poor prognosis, which commonly presents at a younger age than non-small-cell lung carcinoma. We report a rare case of pulmonary blastoma in a 62-year-old man with discoid lupus who presented with chronic cough and pleuritic pain. The 5.3-cm tumor was located in the left upper lobe, invaded the visceral pleura, and adhered to the parietal pleura. The patient underwent a left upper lobectomy and chest wall excision, with adjuvant chemotherapy and radiotherapy.
RobertJPacheJCSeiumYde PerrotMSpiliopoulosA. Pulmonary blastoma: report of five cases and identification of clinical features suggestive of the disease. Eur J Cardiothorac Surg2002; 22: 708–711.
3.
LeeHJGooJMKimKWImJGKimJH. Pulmonary blastoma radiologic findings in five patients. J Clin Imaging2004; 28: 113–118.
4.
KossMTravisWMoranC. Pulmonary sarcomas, blastomas, carcinosarcomas and teratomas. Spencer’s Pathology of Lung, 5th ed. New York: McGraw-Hill, 1996, pp. 1092–1100.
5.
NakataniYMiyagiYTakemuraT. Aberrant nuclear/cytoplasmic localization and gene mutation of beta-catenin in classic pulmonary blastoma: beta-catenin immunostaining is useful for distinguishing between classic pulmonary blastoma and a blastomatoid variant of carcinosarcoma. Am J Surg Pathol2004; 28: 921–927.
