Otolaryngologists-head and neck surgeons and surgical pathologists should be aware of the potential for acinic cell carcinomas to dedifferentiate so that adequate histologic tumor sampling can be performed. Dedifferentiated acinic cell carcinoma is a highly malignant, newly recognized parotid malignancy. Clinical clues that may help identify this more ominous lesion must be recognized.
Get full access to this article
View all access options for this article.
References
1.
BatsakisJG. Tumors of the head and neck: clinical and pathological considerations.2nd ed.Baltimore: Williams & Wilkins Company, 1979: 39–44
2.
ThackrayACLucasRB. Tumors of the major salivary glands. In: Atlas of tumor pathology, Fascicle 10.Washington, D.C.: Armed Forces Institute of Pathology, 1974: 81–90
3.
AbramsAMCornynJScofieldHHHansenLS. Acinic cell adenocarcinoma of the major salivary glands: A clinicopathologic study of 77 cases. Cancer1965; 18: 1145–62
4.
NasseD. Die Geschwülste der Speicheldrüsen und verwandte Tumoren des Kopfes. Arch Klin Chir1892; 44: 233–302
5.
BuxtonRWMaxwellJHFrenchAJ. Surgical treatment of epithelial tumors of the parotid gland. Surg Gynecol Obstet1953; 97: 401–16
6.
FooteFWJrFrazellEL. Tumors of the major salivary glands. Cancer1953; 6: 1065–1133
7.
BatsakisJGChinnERegeziJARepolaDA. The pathology of head and neck tumors: Salivary glands, part 2. Head Neck Surg1978; 1: 167–80
8.
ChometteGAuriolMVaillantJM. Acinic cell tumors of salivary glands: Frequency and morphological study. J Biol Buccale1984; 12: 157–69
9.
EllisGLCorioRL. Acinic cell adenocarcinoma: A clinicopathologic analysis of 294 cases. Cancer1983; 52: 542–9
10.
PerzinKHLiVolsiVA. Acinic cell carcinomas arising in salivary glands: A clinicopathologic study. Cancer1979; 44: 1434–57
11.
SpiroRHHuvosAGStrongEW. Acinic cell carcinoma of salivary origin: A clinicopathologic study of 67 cases. Cancer1978; 41: 924–35
12.
EvansHL. Liposarcoma: A study of 55 cases with a reassessment of its classification. Am J Surg Pathol1979; 3: 507–23
