Two cases of pemphigus vulgaris occurring in young men, aged 24 and 29, are presented. Prior to referral, each patient had persistent oral vesiculobullous and ulcerative mucous membrane lesions for at least six months and was treated with multiple courses of antibiotics and mouthwashes. On initial examination, both patients had the characteristic oral vesiculobullous lesions of pemphigus. A biopsy specimen of an intact vesicle confirmed the diagnosis.
Get full access to this article
View all access options for this article.
References
1.
GellisS, GlassFA: Pemphigus, a survey of 170 patients admitted to Bellevue Hospital from 1911 to 1941. Arch Dermatol Syphil44: 321–336, 1941.
2.
KrainLS: Pemphigus, epidemiologic and survival characteristics of 59 patients, 1955-1973. Arch Dermatol110: 862–865, 1974.
3.
EversoleLR, KenneyBC, SabesWR: Oral lesions as the initial sign in pemphigus vulgaris. Oral Surg33: 354–361, 1972.
4.
ShklarG, CataldoE: Histopathology and cytology of oral lesions of pemphigus. Arch Dermatol101: 635–641, 1970.
5.
HaslerJF: The role of immunofluorescence in the diagnosis of oral vesiculobullous disorders. Oral Surg33: 362–374, 1972.
6.
NallyFF: Pemphigus vulgaris: Report of six cases including a good response with estrogen therapy. Int J Med Sci140: 353–367, 1971.
7.
BlockLJ, CaldarelliDD, HolingerPH: Pemphigus of the air and food passages. Ann Otol Rhinol Laryngol86: 584–587, 1977.
8.
BeesonPB, McDermottW: Textbook of Medicine, ed 15. Philadelphia, WB Saunders Co, 1975, pp 1854–1855.
9.
LeverWF: Methotrexate and prednisone in pemphigus vulgaris. Arch Dermatol106: 491–493, 1972.
10.
LeverWF, Schaumburg-LeverG: Immunosuppressants and prednisone in pemphigus vulgaris. Arch Dermatol113: 1236–1241, 1977.
