Abstract
Objective: Obstructive sleep apnea (OSA) has been associated with metabolic syndrome (MS) and its various components. However, the impact of successful treatment of OSA on MS is still unclear. This study analyzes the prevalence of metabolic syndrome and its various components in patients with OSA and evaluates the impact of uvulopalatopharyngoplasty (UPPP) on MS.
Method: A 3-year retrospective chart review of patients referred to an otolaryngology department for sleep disordered breathing. A total of 134 patients met the inclusion criterion. The diagnosis of MS was established according to National Cholesterol Education Program Adult Treatment Panel III.
Results: According to the AHI, the patients were divided into OSA (mean AHI = 64) and controls (mean AHI = 4.46). The incidence of MS was significantly higher in patients with OSA (72.5%) v/s controls (39.5%). The components of MS which showed significance were fasting glucose (P = .002) and blood pressure (P < .032). The prevalence of MS before and 6 months after UPPP was 71.0% and 60.87% which was not statistically significant. The only component of MS showing significant improvement was blood pressure. (P < .001).
Conclusion: There is a high incidence of metabolic syndrome in patients with OSAS. Although UPPP improved respiratory parameters, it did not have a significant effect on the prevalence of MS. The only component which showed a significant improvement was blood pressure.
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