Abstract
Objective: Determine the impact of endoscopic sinus surgery on pulmonary function in children with cystic fibrosis.
Method: Retrospective chart review of cystic fibrosis patients at a tertiary children’s hospital who underwent endoscopic sinus surgery between 1995 and 2010. Main outcome measures include presurgical and 1- and 6-month postsurgical pulmonary function tests (PFTs).
Results: Sixty-two children underwent 110 endoscopic sinus surgeries. Pre- and post-PFT data (FEVI and FVC) were available for 66 surgeries. Postoperative, only 10 out of 66 children (15%) at 1 month and 11 out of 66 (16%) at 6 months showed improvement following surgery. A total of 41 out of 66 children (62%) at 1 month and 42 out of 66 (64%) at 6 months showed no difference, while 15 out of 66 (23%) at 1 month and 13 out of 66 (20%) at 6 months were worse following surgery. There was no difference in pulmonary function following primary (28/66 [42%]) or revision (38/66 [58%]) surgeries.
Conclusion: Improvement of sinonasal symptoms achieved with endoscopic sinus surgery does not correlate with improvement in pulmonary function as measured by pre- and postoperative pulmonary function testing in children with cystic fibrosis.
Get full access to this article
View all access options for this article.