Abstract
Objective: Studies have shown that nasopharyngeal airway diseases, such as obstructive sleep apnea, are closely associated with cardiovascular diseases. The purpose of this study was to investigate whether there is any impact of septoplasty operation on QTc dispersion (QTcD) in patients with nasal septum deviation.
Method: This study included 28 young deviated nasal septum patients. All patients underwent septoplasty. The QT interval, the heart rate-corrected QT, and the QT dispersion were calculated digitally using computerized electrocardiograms (ECG) by Holter ECG. Heart rates, QT intervals, QTc, and QTcD values were compared preoperatively and one-month postoperatively.
Results: QTcD was measured 62.9 ± 7.9 in young patients with nasal septal deviation. While there was no significant change in ECG QT interval periods obtained from the patients taken after the procedure (354.8 ± 25.7 and 360 ± 25.4, P > .05), there was a significant decrease in QTc values (398 ± 22.9 and 383.7 ± 21.2, P = .013 [<0.05]), and there was a significant decrease in QTcD values (62.9 ± 7.9 and 45.7 ± 6.7, P = .000). In addition, heart rates were significantly decreased after surgery (76.5 ± 13.2 and 67.4 ± 10.4, P = .007).
Conclusion: In our study, QTcD values were increased in young patients with nasal septal deviation. High QTcD value indicates increased heterogeneity of ventricular repolarization. Septoplasty is important for young people with nasal deviations to provide improvement of QTc dispersion. Nasopharyngeal airway diseases have negative effects on myocardial repolarization.
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