Inadequate social support and poor communications with health care providers can affect adherence to antiretroviral therapy. The magnitude of independent effects of these factors on adherence is not fully known. This study examined the relationship of perceived emotional or informational social support from family and friends, quality of physician-patient communications and relationships, and medication adherence in a sample of low-income, Spanishspeaking, HIV-positive Latino men and women receiving treatment in community-based clinics (n = 85). Results of the study indicated that, whereas emotional or informational support was significantly associated with level of dose adherence (OR, 1.04, 95% CI, 1.01-1.08;p = .03), quality of physician-patient communications or relationships was significantly associated with adherence to medication schedule,t(6, 71) = 4.45,p < .001. Quality of patient-physician relationship accounted for 22% of the variance in adherence to medication schedule. Both kinds of support were associated with better adherence in this population but may affect adherence behaviors in different ways.
Antonovsky, A. (1979). Health, stress, and coping. San Francisco: Jossey-Bass.
2.
Bakken, S., Holzemer, W. L., Brown, M. A., Powell-Cope, G. M., Turner, J. G., Inouye, J., et al. (2000). Relationships between perception of engagement with health care provider and demographic characteristics, health status, and adherence to therapeutic regimens in persons with HIV/AIDS. AIDS Patient Care and STDS, 14, 189-197.
3.
Bandura, A. (1986). Social foundations of thought and action. Englewood Cliffs, NJ: Prentice Hall.
4.
Berg, K. M., Demas, P. A., Howard, A. A., Schoenbaum, E. E., Gourevitch, M. N., & Arnsten, J. H. (2004). Gender differences in factors associated with adherence to antiretroviral therapy. Journal of General Internal Medicine, 19, 1111-1117.
5.
Burak, J. H., Barrett, D. C., Stall, R. D., Chesney, M. A., Ekstrand, M. L.,& Coates, T. J. (1993). Depressive symptoms and CD4 lymphocyte decline among HIV-infected men. Journal of the American Medical Association, 270, 2568-2573.
6.
Catz, S. L., Heckman, T. G., Kochman, A., & DiMarco, M. (2001). Rates and correlates of HIV treatment adherence among late middle-aged and older adults living with HIV disease. Psychology of Health and Medicine, 6, 47-58.
7.
Catz, S. L., Kelly, J. A., Bogart, L. M., Benotsch, E. G.,& Mc Auliffe, T. L. (2000). Patterns, correlates, and barriers to medication adherence among persons prescribed new treatments for HIV disease. Health Psychology, 19, 124-133.
8.
Centers for Disease Control and Prevention (CDC). (2002). HIV/AIDS among Hispanics in the United States. Retrieved March 11, 2004, from http://www.cdc.gov/HIV/pubs/facts/Hispanic.html
9.
Centers for Disease Control and Prevention (CDC). (2003). HIV/AIDS surveillance report. Retrieved March 11, 2004, from http://www.cdc.gov/hiv/stats/hasrlink.htm
10.
Chesney, M. A. (2003). Adherence to HAART regimens. AIDS Patient Care and STDS, 17, 169-177.
11.
Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., Zwickl, B., et al. (2000).Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG adherence instruments. Patient Care Committee & Adherence Working Group of the Outcomes Committee of the Adult AIDS Clinical Trials Group (AACTG). AIDS Care, 12, 255-266.
12.
Diaz, R. M. (1998). Latino gay men and HIV: Culture, sexuality, and risk behavior. New York: Routledge.
13.
Gao, X., Nau, D. P., Rosenbluth, S. A., Scott, V.,& Woodward, C. (2000). The relationship of diseases severity, health beliefs, and medication adherence among HIV patients. AIDS Care, 12, 387-398.
14.
Garcia, P. R.,& Cote, J. K. (2003). Factors affecting adherence to antiretroviral therapy in people living with HIV/AIDS. Journal of the Association of Nurses in AIDS Care, 14, 37-45.
15.
Haubrich, R., Little, S., Currier, J., Forthal, D., Kemper, C., Beall, G., et al. (1999).The value of patient-reported adherence to antiretroviral therapy in predicting virologic and immunologic response during unrestricted therapy. AIDS, 13, 1099-1107.
16.
Holzemer, W. L., Corless, K. M., Nokes, J. G., Turner, M. A., Brown, G. M., Powell-Cope, G. M., et al. (1999). Predictors of self-reported adherence in persons living with HIV disease. AIDS Patient Care and STDS, 13, 185-197.
17.
Ickovics, J. R.,& Meisler, A. W. (1997). Adherence in AIDS clinical trials: Aframework for clinical research and clinical care. Journal of Clinical Epidemiology, 50, 385-391.
18.
Johnson, M. O., Catz, S. L., Remien, R. H., Rotheram-Borus, M. J., Morin, S. F., Charlebois, E., et al. (2003). Theory-guided, empirically supported avenues for intervention on HIV medication nonadherence: Findings from the Healthy Living Project. AIDS Patient Care and STDS, 17, 645-656.
19.
Kalichman, S. C., Ramachandran, B., & Catz, S. (1999). Adherence to combination antiretroviral therapies in HIV patients of low health literacy. Journal of General Internal Medicine, 14, 267-273.
20.
Lazarus, R. S., & Folkman, S. (1984). Stress, appraisal, and coping. New York: Springer.
21.
Martini, M., Nasta, P., Ricci, E., Parazzini, F.,& Agnoletto, V. (2000). Perception of disease and therapy are factors influencing adherence to antiretroviral therapy. Sexually Transmitted Diseases, 76, 496-497.
22.
Miller, W. R.,& Rollnick, S. R. (2002). Motivational interviewing: Preparing people for change (2nd ed.). New York: Guilford.
23.
Morales, L. S., Cunningham, W. E., Brown, J. A., Liu, H., & Hays, R. (1999). Are Latinos less satisfied with communication from health care providers?Journal of General Internal Medicine, 14, 409-417.
24.
Murphy, D. A., Lu, M. C., Martin, D., Hoffman, D.,& Marelich, W. D. (2002). Results of a pilot intervention trial to improve antiretroviral adherence among HIV-positive patients. Journal of the Association of Nurses in AIDS Care, 13, 57-69.
25.
Nieuwkerk, P. T.,& Oort, F. J. (2005). Self-reported adherence to antiretroviral therapy for HIV-1 Infection and virologic treatment response—A meta-analysis. Journal of Acquired Immune Deficiency Syndrome, 38, 445-448.
26.
Paterson, D. L., Swindells, S., Mohr, J., Brester, M., Vergis, E. N., Squier, C., et al. (2000). Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Annals of Internal Medicine, 133, 21-30.
27.
Power, R., Koopman, C., Volk, J., Israilski, D. M., Stone, L., Chesney, M. A., et al. (2003). Social support, substance use, and denial in relationship to antiretroviral treatment adherence among HIV-infected persons. AIDS Patient Care and STDS, 17, 245-252.
28.
Radloff, L. S. (1977). The CES-D scale: Aself-report depression scale for research in the general population. Applied Psychological Measurement, 1, 385-401.
29.
Reynolds, N. R. (2004). Adherence to antiretroviral therapies: State of the science. Current HIV Research, 2, 207-214.
30.
Roberts, K. J. (2000). Barriers to and facilitators of HIV-positive patients' adherence to antiretroviral treatment regimens. AIDS Patient Care and STDS, 14, 155-168.
31.
Rotter, J. B. (1982). The development and applications of social learning theory: Selected papers. New York: Praeger.
32.
Russell, J., Krantz, S., & Neville, S. (2004). The patient-provider relationship and adherence to highly active antiretroviral therapy. Journal of the Association of Nurses in AIDS Care, 15, 40-47.
33.
Schneider, J., Kaplan, S. H., Greenfield, S., Li, W., & Wilson, I. B. (2004). Better physicianpatient relationships are associated with higher reported adherence to antiretroviral therapy in patients with HIV infection. Journal of General Internal Medicine, 19, 1096-1103.
34.
Sherbourne, C. D., & Stewart, A. L. (1991). The MOS Social Support Survey. Social Science Medicine, 32, 705-714.
35.
Simoni, J., Frick, P. A., Lockhart, D., & Liebovitz, D. (2002). Mediators of social support and antiretroviral adherence among an indigent population in New York City. AIDS Patient Care and STDS, 16, 431-439.
36.
Simoni, J., Frick, P. A., Pantalone, D. W., & Turner, B. J. (2003). Antiretroviral adherence interventions: A review of current literature and ongoing studies. Topics in HIV Medicine, 11, 185-198.
37.
Spire, B., Duran, S., Souville, M., Leport, C., Raffii, F., Moatti, J. P., et al. (2002). Adherence to highly active antiretroviral therapies (HAART) in HIV-infected patients: From a predictive to a dynamic approach. Social Science and Medicine, 54, 1481-1496.
38.
Thoits, P. A. (1986). Social support as coping assistance. Journal of Consulting and Clinical Psychology, 54, 416-423.
39.
Wagner, G. J. (2002). Predictors of antiretroviral adherence as measured by self-report, electronic monitoring, and medication diaries. AIDS Patient Care and STDS, 16, 599-608.
40.
Yu, D. S., Lee, D. T.,& Woo, J. (2004). Psychometric testing of the Chinese version of the medical outcomes study social support survey (MOS-SSS-C). Research in Nursing and Health, 27, 135-143.
