The objective of the present study was to investigate the relationship between inflammatory, metabolic, and anthropometrical parameters of elderly women with insulin resistance (IR) and without insulin resistance (WIR). One hundred and seventy-two elderly women aged 67.5 (± 5 years) were submitted to anthropometrical analysis, by dual energy X-ray absorptiometry, and biochemistry tests such as lipidogram, fasting blood glucose, glycosylated hemoglobin, insulin, C-reactive protein, Interleukin-6, tumor necrosis factor-alpha, and Interferon-gamma. Body mass index, waist circumference, waist-to-hip ratio, body fat mass, triglycerides, very low density lipoprotein, fasting glucose, and insulin were significantly higher, while lean body mass was lower (p < 0.05), in elderly with IR as compared to WIR. There was no significant difference between groups in the inflammatory parameters. Elderly women with IR present increased anthropometrical and metabolic parameters that predispose them to several chronic nontransmissible diseases. Additional inflammatory parameters should be used in elderly women to define an optimal relationship with insulin resistance in clinical practice.
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