Multiple Factors Affecting Health-Related Quality of Life in Women With Chronic Multisite Musculoskeletal Pain: A Cross-Sectional Study in Ankara,Turkey

Abstract

Although chronic multi-site musculoskeletal pain is known to cause decreased physical function and impair work and social life, there is insufficient research about its impact on health-related quality of life (HRQoL) in women. The aim of this study was to investigate multiple factors affecting HRQoL in women with chronic multi-site musculoskeletal pain. This study included 227 women with two or more musculoskeletal areas which were painful during the last 3 months. The HRQoL and musculoskeletal system symptoms were evaluated with the Nottingham Health Profile (NHP) and the Nordic Musculoskeletal Questionnaire (NMQ), respectively. Physical activity level, social functionality and depressive symptoms were assessed with the International Physical Activity Questionnaire-Short Form (IPAQ- SF), Social Functioning Scale (SFS) and Beck Depression Inventory (BDI), respectively. Significant predictors for the total score on the NHP were found to be the number of children (p < 0.001), social engagement/withdrawal scale (p:0.094), the number of regions with musculoskeletal pain during the last year (p:0.002) and last 7 days (p:0.036), depressive symptoms (p < 0.001), current employment status (p:0.084), and the presence of chronic disease (p < 0.001). The results of this study demonstrated that both sociodemographic characteristics, and social and psychological factors may affect the HRQoL in women with chronic multi-site musculoskeletal pain.

Keywords

adult health pain quality of life women

Get full access to this article

View all access options for this article.

References

Aktürk

Dağdeviren

Türe

Tuğlu

(2005). The reliability and validity analysis of the Turkish version of Beck depression inventory for primary care. Turkish Journal of Family Practice, 9(3), 117–122.

Bakas

McLennon

S. M.

Carpenter

J. S.

Buelow

J. M.

Otte

J. L.

Hanna

K. M.

Ellett

M. L.

Hadler

K. A.

Welch

J. L.

(2012). Systematic review of health-related quality of life models. Health and Quality of Life Outcomes, 10(1), 1–12. http://www.hqlo.com/content/10/1/134

Bingefors

Isacson

(2004). Epidemiology, co-morbidity, and impact on health-related quality of life of self-reported headache and musculoskeletal pain—A gender perspective. European Journal of Pain, 8(5), 435–450. https://doi.org/10.1016/j.ejpain.2004.01.005

Bot

S. D.

van der Waal

J. M.

Terwee

C. B.

van der Windt

D. A. W. M.

Bouter

L. M.

Dekker

(2005). Course and prognosis of elbow complaints: A cohort study in general practice. Annals of the Rheumatic Diseases, 64(9), 1331–1336. https://doi.org/10.1136/ard.2004.030320

Caldwell

Hart-Johnson

Green

C. R.

(2009). Body mass index and quality of life: Examining blacks and whites with chronic pain. The Journal of Pain, 10(1), 60–67. https://doi.org/10.1016/j.jpain.2008.07.005

Carr

Freedman

V. A.

Cornman

J. C.

Schwarz

(2014). Happy marriage, happy life? Marital quality and subjective well-being in later life. Journal of Marriage and Family, 76(5), 930–948. https://doi.org/10.1111/jomf.12133

Chan

E. H.

Kong

S. D.

Park

S. H.

Song

Y. J.

Demetriou

E. A.

Pepper

K. L.

Glozier

Hickie

I. B.

Guastella

A. J.

(2019). Validation of the social functioning scale: Comparison and evaluation in early psychosis, autism spectrum disorder and social anxiety disorder. Psychiatry Research, 276, 45–55. https://doi.org/10.1016/j.psychres.2019.03.037

Cherry

K. E.

Walker

E. J.

Brown

J. S.

Volaufova

LaMotte

L. R.

Welsh

D. A.

L. J.

Jazwinski

S. M.

Ellis

Wood

R. H.

Frisard

M. I.

(2013). Social engagement and health in younger, older, and oldest-old adults in the Louisiana healthy aging study. Journal of Applied Gerontology, 32(1), 51–75. https://doi.org/10.1177/0733464811409034

Da Luz

R. A.

de Deus

J. M.

Conde

D. M.

(2018). Quality of life and associated factors in Brazilian women with chronic pelvic pain. Journal of Pain Research, 11, 1367–1374. https://doi.org/10.2147/JPR.S168402

10.

Elliott

A. M.

Smith

B. H.

Hannaford

P. C.

Smith

W. C.

Chambers

W. A.

(2002). The course of chronic pain in the community: Results of a 4-year follow-up study. Pain, 99(1–2), 299–307. https://doi.org/10.1016/S0304-3959(02)00138-0

11.

Eum

Kim

(2021). Relationship between active aging and quality of life in middle-aged and older Koreans: Analysis of the 2013–2018 KNHANES. Healthcare, 9, 240–251. https://doi.org/10.3390/healthcare9020240

12.

Ferrans

C. E.

Zerwic

J. J.

Wilbur

J. E.

Larson

J. L.

(2005). Conceptual model of health-related quality of life. Journal of Nursing Scholarship, 37(4), 336–342. https://doi.org/10.1111/j.1547-5069.2005.00058.x

13.

Fillingim

R. B.

Edwards

R. R.

Powell

(2000). Sex-dependent effects of reported familial pain history on recent pain complaints and experimental pain responses. Pain, 86(1-2), 87–94. https://doi.org/10.1016/S0304-3959(00)00239-6

14.

Finney

Dziedzic

K. S.

Lewis

Healey

(2017). Multisite peripheral joint pain: A cross-sectional study of prevalence and impact on general health, quality of life, pain intensity and consultation behaviour. BMC Musculoskeletal Disorders, 18(1), 1–8. https://doi.org/10.1186/s12891-017-1896-3

15.

Generaal

Vogelzangs

Macfarlane

G. J.

Geenen

Smit

J. H.

Penninx

B. W.

Dekker

. (2014). Reduced hypothalamic-pituitary-adrenal axis activity in chronic multi-site musculoskeletal pain: Partly masked by depressive and anxiety disorders. BMC Musculoskeletal Disorders, 15(1), 227–238. http://www.biomedcentral.com/1471-2474/15/227

16.

Generaal

Vogelzangs

Penninx

B. W.

Dekker

(2017). Insomnia, sleep duration, depressive symptoms, and the onset of chronic multisite musculoskeletal pain. Sleep, 40(1), 1–10. https://doi.org/10.1093/sleep/zsw030

17.

Green

S. B.

(1991). How many subjects does it take to do a regression analysis. Multivariate Behavioral Research, 26(3), 499–510. https://doi.org/10.1207/s15327906mbr2603_7

18.

Haas

B. K.

(1999). A multidisciplinary concept analysis of quality of life. Western Journal of Nursing Research, 21(6), 728–742. https://doi.org/10.1177/01939459922044153

19.

Herin

Vézina

Thaon

Soulat

J. M.

Paris

(2014). Predictive risk factors for chronic regional and multisite musculoskeletal pain: A 5-year prospective study in a working population. Pain, 155(5), 937–943. https://doi.org/10.1016/j.pain.2014.01.033

20.

Hill

Lewis

Papageorgiou

A. C.

Dziedzic

Croft

(2004). Predicting persistent neck pain: A 1-year follow-up of a population cohort. Spine, 29(15), 1648–1654. https://doi.org/10.1097/01.BRS.0000132307.06321.3C

21.

Jönsson

Hansson

E. E.

Thorstensson

C. A.

Eek

Bergman

Dahlberg

L. E.

(2018). The effect of education and supervised exercise on physical activity, pain, quality of life and self-efficacy-an intervention study with a reference group. BMC Musculoskeletal Disorders, 19(1), 1–11. https://doi.org/10.1186/s12891-018-2098-3

22.

Kahraman

Genç

Göz

(2016). The Nordic Musculoskeletal Questionnaire: Cross-cultural adaptation into Turkish assessing its psychometric properties. Disability and Rehabilitation, 38(21), 2153–2160. https://doi.org/10.3109/09638288.2015.1114034

23.

Kamaleri

Natvig

Ihlebaek

C. M.

Bruusgaard

(2008). Localized or widespread musculoskeletal pain: Does it matter? Pain, 138(1), 41–46. https://doi.org/10.1016/j.pain.2007.11.002

24.

Kamaleri

Natvig

Ihlebaek

C. M.

Bruusgaard

(2009). Does the number of musculoskeletal pain sites predict work disability? A 14-year prospective study. European Journal of Pain, 13(4), 426–430. https://doi.org/10.1016/j.ejpain.2008.05.009

25.

Kelly

Yang

Chen

C. S.

Reynolds

(2008). Global burden of obesity in 2005 and projections to 2030. International Journal of Obesity, 32(9), 1431–1437. https://www.nature.com/articles/ijo2008102?type=access_denied

26.

Kücükdeveci

A. A.

McKenna

S. P.

Kutlay

Gürsel

Whalley

Arasil

(2000). The development and psychometric assessment of the Turkish version of the Nottingham Health Profile. International Journal of Rehabilitation Research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation, 23(1), 31–38. https://doi.org/10.1097/00004356-200023010-00004

27.

LeResche

(2000). Epidemiologic perspectives on sex differences in pain. Sex, Gender, and Pain, 233–249.

28.

Holm

Gulanick

Lanuza

(2000). Perimenopause and the quality of life. Clinical Nursing Research, 9(1), 6–23. https://doi.org/10.1177/105477380000900102

29.

Lin

H. H. S.

Naimi

A. I.

Brooks

M. M.

Richardson

G. A.

Burke

J. G.

Bromberger

J. T.

(2018). Child maltreatment as a social determinant of midlife health-related quality of life in women: Do psychosocial factors explain this association? Quality of Life Research, 27(12), 3243–3254. https://doi.org/10.1007/s11136-018-1937-x

30.

Madrid-Valero

J. J.

Martínez-Selva

J. M.

Couto

B. R. D.

Sánchez-Romera

J. F.

Ordoñana

J. R.

(2017). Age and gender effects on the prevalence of poor sleep quality in the adult population. Gaceta Sanitaria, 31, 18–22. https://doi.org/10.1016/j.gaceta.2016.05.013

31.

Magni

Moreschi

Rigatti-Luchini

Merskey

(1994). Prospective study on the relationship between depressive symptoms and chronic musculoskeletal pain. Pain, 56(3), 289–297. https://doi.org/10.1016/0304-3959(94)90167-8

32.

Megari

(2013). Quality of life in chronic disease patients. Health Psychology Research, 1(3), 141–148. https://doi.org/10.4081/hpr.2013.e27

33.

Menec

V. H.

(2003). The relation between everyday activities and successful aging: A 6-year longitudinal study. The Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 58(2), S74–S82. https://doi.org/10.1093/geronb/58.2.S74

34.

Muraki

Akune

Oka

En-Yo

Yoshida

Saika

Suzuki

Yoshida

Ishibashi

Tokimura

Yamamoto

Nakamura

Kawaguchi

Yoshimura

(2010). Association of radiographic and symptomatic knee osteoarthritis with health-related quality of life in a population-based cohort study in Japan: The ROAD study. Osteoarthritis and Cartilage, 18(9), 1227–1234. https://doi.org/10.1016/j.joca.2010.06.001

35.

Natvig

Bruusgaard

Eriksen

(2001). Localized low back pain and low back pain as part of widespread musculoskeletal pain: Two different disorders? A cross-sectional population study. Journal of Rehabilitation Medicine, 33(1), 21–25.

36.

Natvig

Eriksen

Bruusgaard

(2002). Low back pain as a predictor of long-term work disability. Scandinavian Journal of Public Health, 30(4), 288–292. https://doi.org/10.1080/14034940210133951

37.

Nicholl

B. I.

Macfarlane

G. J.

Davies

K. A.

Morriss

Dickens

McBeth

(2009). Premorbid psychosocial factors are associated with poor health-related quality of life in subjects with new onset of chronic widespread pain—Results from the EPIFUND study. Pain, 141(1–2), 119–126. https://doi.org/10.1016/j.pain.2008.10.022

38.

Nishida

Tanaka

Sakakibara

(2018). Factors associated with quality of life among mothers rearing 4-and 18-month old infants in Japan. Maternal and Child Health Journal, 22(8), 1217–1225. https://doi.org/10.1007/s10995-018-2493-2

39.

Niv

Kreitler

(2001). Pain and quality of life. Pain Practice, 1(2), 150–161. https://doi.org/10.1046/j.1533-2500.2001.01016.x

40.

Orenius

Koskela

Koho

Pohjolainen

Kautiainen

Haanpää

Hurri

(2013). Anxiety and depression are independent predictors of quality of life of patients with chronic musculoskeletal pain. Journal of Health Psychology, 18(2), 167–175. https://doi.org/10.1177/1359105311434605

41.

Pehlivan

Karadakovan

(2019). Effects of aromatherapy massage on pain, functional state, and quality of life in an elderly individual with knee osteoarthritis. Japan Journal of Nursing Science, 16(4), 450–458. https://doi.org/10.1111/jjns.12254

42.

Pereira

R. J.

Cotta

R. M. M.

Franceschini

S. D. C. C.

Ribeiro

R. D. C. L.

Sampaio

R. F.

Priore

S. E.

Cecon

P. R.

(2006). Contribution of the physical, social, psychological and environmental domains to overall quality of life of the elderly. Revista de Psiquiatria do Rio Grande do Sul, 28(1), 27–38. https://doi.org/10.1590/S0101-81082006000100005

43.

Picavet

H. S. J.

Hoeymans

(2004). Health related quality of life in multiple musculoskeletal diseases: SF-36 and EQ-5D in the DMC3 study. Annals of the Rheumatic Diseases, 63(6), 723–729. https://doi.org/10.1136/ard.2003.010769

44.

Rathleff

M. S.

Roos

E. M.

Olesen

J. L.

Rasmussen

. (2013). High prevalence of daily and multi-site pain–a cross-sectional population-based study among 3000 Danish adolescents. BMC Pediatrics, 13(1), 191. http://www.biomedcentral.com/1471-2431/13/191

45.

Rijken

Van Kerkhof

Dekker

Schellevis

F. G.

(2005). Comorbidity of chronic diseases. Quality of Life Research, 14(1), 45–55. https://doi.org/10.1007/s11136-004-0616-2

46.

Sach

T. H.

Barton

G. R.

Doherty

Muir

K. R.

Jenkinson

Avery

A. J.

(2007). The relationship between body mass index and health-related quality of life: Comparing the EQ-5d, Euroqol VAS and SF-6d. International Journal of Obesity, 31(1), 189–196. https://doi.org/10.1038/sj.ijo.0803365

47.

Saglam

Arikan

Savci

Inal-Ince

Bosnak-Guclu

Karabulut

Tokgozoglu

(2010). International physical activity questionnaire: Reliability and validity of the Turkish version. Perceptual and Motor Skills, 111(1), 278–284. https://doi.org/10.2466/06.08.PMS.111.4.278-284

48.

Salaffi

De Angelis

Stancati

Grassi

Pain

(2005). Health-related quality of life in multiple musculoskeletal conditions: A cross-sectional population based epidemiological study: II. The MAPPING study. Clinical and Experimental Rheumatology, 23(6), 829–839.

49.

Saunders

Von Korff

LeResche

Mancl

(2007). Relationship of common pain conditions in mothers and children. The Clinical Journal of Pain, 23(3), 204–213. https://doi.org/0.1097/AJP.0b013e31802d7807

50.

Schwingel

Niti

M. M.

Tang

T. P.

(2009). Continued work employment and volunteerism and mental well-being of older adults: Singapore longitudinal ageing studies. Age and Ageing, 38(5), 531–537. https://doi.org/10.1093/ageing/afp089

51.

Shih

Simon

P. A.

(2008). Health-related quality of life among adults with serious psychological distress and chronic medical conditions. Quality of Life Research, 17(4), 521–528. https://doi.org/10.1007/s11136-008-9330-9

52.

Tander

Cengiz

Alayli

İlhanli

İ.

Canbaz

Canturk

(2008). A comparative evaluation of health related quality of life and depression in patients with fibromyalgia syndrome and rheumatoid arthritis. Rheumatology International, 28(9), 859–865. https://doi.org/10.1007/s00296-008-0551-6

53.

Telci

E. A.

Yarar

Cavlak

Atalay

O. T.

(2018). Comparison of musculoskeletal pain distribution, quality of life and hopelessness level in mothers with disabled children in different ambulation levels. Journal of Back and Musculoskeletal Rehabilitation, 31(2), 305–313. https://doi.org/10.3233/BMR-169709

54.

Trombetti

Reid

K. F.

Hars

Herrmann

F. R.

Pasha

Phillips

E. M.

Fielding

R. A.

(2016). Age-associated declines in muscle mass, strength, power, and physical performance: Impact on fear of falling and quality of life. Osteoporosis International, 27(2), 463–471. https://doi.org/10.1007/s00198-015-3236-5

55.

van der Waal

J. M.

Bot

S. D.

Terwee

C. B.

van der Windt

D. A.

Scholten

R. J.

Bouter

L. M.

Dekker

(2005). Course and prognosis of knee complaints in general practice. Arthritis Care & Research: Official Journal of the American College of Rheumatology, 53(6), 920–930. https://doi.org/10.1002/art.21581

56.

Verbrugge

L. M.

(1985). Gender and health: An update on hypotheses and evidence. Journal of Health and Social Behavior, 156–182. https://doi.org/10.2307/2136750

57.

Verbunt

J. A.

Pernot

D. H.

Smeets

R. J.

(2008). Disability and quality of life in patients with fibromyalgia. Health and Quality of Life Outcomes, 6(1), 1–8. https://doi.org/10.1186/1477-7525-6-8

58.

Wettstein

Eich

Bieber

Tesarz

(2019). Pain intensity, disability, and quality of life in patients with chronic low back pain: Does age matter? Pain Medicine, 20(3), 464–475. https://doi.org/10.1093/pm/pny062

59.

Wolfe

Hawley

D. J.

Wilson

(1996). The prevalence and meaning of fatigue in rheumatic disease. The Journal of Rheumatology, 23(8), 1407–1417.

60.

Yalcinkaya

Ucok

Ulasli

A. M.

Coban

N. F.

Aydin

Kaya

Akkan

Tugrul Senay

(2017). Do male and female patients with chronic neck pain really have different health-related physical fitness, depression, anxiety and quality of life parameters? International Journal of Rheumatic Diseases, 20(9), 1079–1087. https://doi.org/10.1111/1756-185X.12389

61.

Yaprak Erakay

Gülseren

Ş.

(2002). Şizofreni tanılı hastalarda Sosyal İşlevsellik Ölçeği Türkçe Formu’nun geçerlilik ve güvenilirliğinin araştırılması [Investigation of the validity and reliability of the Turkish form of the social functioning scale in patients with schizophrenia]. Bahar Sempozyumları VI, Kongre Özet Kitabı, 134–135.

62.

Yurt

Şener

Yakut

(2018). The effect of different foot orthoses on pain and health related quality of life in painful flexible flat foot: A randomized controlled trial. European Journal of Physical and Rehabilitation Medicine, 55(1), 95–102. https://doi.org/10.23736/s1973-9087.18.05108-0

63.

Zautra

A. J.

Hamilton

Yocum

(2000). Patterns of positive social engagement among women with rheumatoid arthritis. The Occupational Therapy Journal of Research, 20(1_suppl), 21S–40S. https://doi.org/10.1177/15394492000200S103

64.

Zhang

Guo

Zhang

Chen

Zhou

Qian

(2017). Health-related quality of life among adults with and without hypertension: A population-based survey using EQ-5D in Shandong, China. Scientific Reports, 7(1), 1–7. https://doi.org/10.1038/s41598-017-15083-4

Supplementary Material

Please find the following supplemental material available below.

For Open Access articles published under a Creative Commons License, all supplemental material carries the same license as the article it is associated with.

For non-Open Access articles published, all supplemental material carries a non-exclusive license, and permission requests for re-use of supplemental material or any part of supplemental material shall be sent directly to the copyright owner as specified in the copyright notice associated with the article.

0.00 MB

0.01 MB