The commentary addresses discussion regarding the duration of infusion for lipid injectable emulsions (ILEs; previously known as intravenous fat emulsion) when administered separately from amino acids and dextrose (2:1) admixtures. The article by Mundi et al describes the administration time of ILEs administered separately as up to 24 hours, while previous American Society for Parenteral and Enteral Nutrition documents have outlined the infusion time not to exceed 12 hours.
MundiMSNystromEMHurleyDLMcMahonMM. Management of parenteral nutrition in hospitalized adult patients [published online September1, 2016]. JPEN J Parenter Enteral Nutr.
2.
MirtalloJCanadaTJohnsonD; ASPEN Board of Directors and Task Force for the Revision of Safe Practices for Parenteral Nutrition. Safe practices for parenteral nutrition [published correction appears in JPEN J Parenter Enteral Nutr. 2006;30:177]. JPEN J Parenter Enteral Nutr. 2004;28:S39-S70.
BoullataJIGilbertKSacksGASPEN clinical guidelines: parenteral nutrition ordering, order review, compounding, labeling, and dispensing. JPEN J Parenter Enteral Nutr. 2014;38(3):334-377.
5.
EbbertMLFarrajMHwangLT.The incidence and clinical significance of intravenous fat emulsions contamination during infusion. JPEN J Parenter Enteral Nutr. 1987;11(1):42-45.
6.
CrillCMHakEBRobinsonLAHelmsRA.Evaluation of microbial contamination associated with different preparation methods for neonatal intravenous fat emulsion infusion. Am J Health Syst Pharm. 2010;67(11):914-918.
7.
ReiterPD.Sterility of intravenous fat emulsion in plastic syringes. Am J Health Syst Pharm. 2002;59(19);1857-1859.
8.
ReiterPDRoblesJDowellEB.Effect of 24-hour intravenous tubing set change on the sterility of repackaged fat emulsion in neonates. Ann Pharmacother. 2004;38(10):1603-1607.
9.
YbarraJVRoseWECurtisCSSacksGS.Sterility of pediatric lipid emulsions repackaged by an automated compounding device. JPEN J Parenter Enteral Nutr. 2011;35(3):391-394.
10.
GorskiLHadawayLHagleMEMcGoldrickMOrrMDoellmanD.Infusion therapy standards of practice. J Infus Nurs. 2016;39(suppl 1):S1-S159.
11.
Centers for Disease Control and Prevention. Guidelines for the prevention of intravascular catheter-related infections. MMWR. 2002; 51:RR-10.
12.
O’GradyNPAlexanderMBurnsLAGuidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis. 2011;52(9):e162-e193.