A 73-year-old man was referred to us for evaluation of extensive nasal crusting and progressive erosion of the nasal midline structures. Clinical examination suggested that the patient had a T-cell lymphoma, a suspicion that was confirmed on immunohistochemical analysis. The patient was treated with combination chemo- and radiotherapy and exhibited a marked response. At the 14-month followup, he remained disease-free.
References
1.
ClearyK.R., BatsakisJ.G.Sinonasal lymphomas. Ann Otol Rhinol Laryngol1994; 103: 911–4.
2.
AbbondanzoS.L., WenigB.M.Non-Hodgkin's lymphoma of the sinonasal tract. A clinicopathologic and immunophenotypic study of 120 cases. Cancer1995; 75: 1281–91.
3.
WeissL.M., ArberD.A., StricklerJ.G.Nasal T-cell lymphoma. Ann Oncol1994; 5(Suppl 1): S39–S42.
4.
SakataK., HareyamaM., OhuchiA.Treatment of lethal midline granuloma type nasal T-cell lymphoma. Acta Oncol1997; 36: 307–11.
5.
RatechH., BurkeJ.S., BlayneyD.W.A clinicopathologic study of malignant lymphomas of the nose, paranasal sinuses, and hard palate, including cases of lethal midline granuloma. Cancer1989; 64: 2525–31.
6.
HartigG., MontoneK., WasikM.Nasal T-cell lymphoma and the lethal midline granuloma syndrome. Otolaryngol Head Neck Surg1996; 114: 653–6.
