As the US population grows older, there is an increasing need to understand how drugs work in the elderly. Bodily accommodations to aging, but more importantly, disease states that occur in the elderly, must be studied to ascertain how drugs affect health and well-being. Assuring proper testing and surveillance of drug use, as well as effective clinical research in the elderly, are important means to this end.
LamyPeter P: Classification of drug interactions. Drug Inf J, 1972;6(1):99.
2.
RodehefferRichard JGerstenblithGaryBeckerLewisFlegJeromeWeisfeldt, Myron, and Lakatta, Edward, Exercise cardiac output is maintained with advancing age in healthy human subjects: cardiac dilation and increased stroke volume compensate for a diminished heart rate. Circulation, 1984;69:2.
3.
CreasyHelenRapoportStanley I: The Aging Brain. Annals of Neurology. Boston; Little, Brown, & Company, 1985.
4.
ShockNWAndresRNorrisAHTobinJD: Patterns of Longitudinal Changes in Renal Function. Recent Advance in Gerontology, XI International Congress of Gerontology, 1979.
5.
TzankoffSPFlegJeromeNorrisAHLakattaEdward, Age-related increase of plasma catecholamines in response to dynamic exercise in healthy adult men. Physiologist, 1980; 23:(40) 50.
