Motor stereotypies,Dhat syndrome,and gaming disorder: A masquerading presentation of Wilson's disease

Abstract

Wilson's disease, a rare genetic disorder caused by ATP7B gene mutations, disrupts copper metabolism, often presenting with psychiatric symptoms in 20–30% of cases before diagnosis. Diagnostic challenges arise owing to non-specific symptoms, leading to potential misdiagnosis. Dhat syndrome, a culture-bound syndrome prevalent in the Indian subcontinent, involves distress over perceived semen loss and, thus, the loss of vitality. We report a case of a young male with dhat syndrome, asymmetrical hand movements, behavioural changes, and gaming disorder who, after long being treated for functional neurological disorder, was later diagnosed with Wilson's disease after a comprehensive evaluation.