Tuberculosis (TB) is a great mimic of many diseases and may present a dilemma in diagnosis. Sebaceous cyst is the commonest swelling that occurs in the scrotal skin. We present a 23-year-old patient who presented with a painful hard scrotal skin nodule, clinically diagnosed to be an infected calcified sebaceous cyst, excised and reported to be due to TB. Nodular scrotal skin TB is extremely rare but should nonetheless be considered as a differential diagnosis in regions where it is prevalent. Thus, excision of any suspicious nodule is indicated.
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