In a volunteer study stanozolol was given in a dosage of 5mg twice per day for six weeks. A variety of parameters in blood coagulation and fibrinolysis were measured. Significant stimulation of the fibrinolytic system was found in seven days and this was associated with a significant fall in the levels of fibrinogen and alpha 2-macroglobulin. No major side effects were observed.
DavidsonJFLockheadMMcDonaldGAMcNicolGP. Fibrinolytic enhancement by stanozolol: a double blind trial. Brit J Haematol1972; 22: 543–559.
2.
WalkerIDDavidsonJF. Long-term fibrinolytic enhancement with anabolic steroid therapy: A five year study. In: DavidsonJFRowanRMSamamaMMDesnoyersPC, eds. Progress in Chemical Fibrinolysis and Thrombolysis, vol. 3. New York: Raven Press, 1978; 491–499.
3.
CunliffeWJDodmanRRobertsBETebbsEM. Clinical and laboratory double-blind investigation of fibrinolytic therapy of cutaneous vasculitis. In: DavidsonJFSamamaMMDesnoyersPC, eds. Progress in Chemical Fibrinolysis and Thrombolysis, vol. 1. New York: Raven Press, 1975; 325–332.
4.
BuckellM. The effect of citrate on euglobulin methods of estimating fibrinolytic activity. J Clin Path1958; 11: 403–407.
5.
EllisBCStranskyA. A quick and accurate method for the determination of fibrinogen in plasma. J Lab Clin Med1961; 58: 477–501.
6.
AustinDRhymesA. A laboratory manual of blood coagulation. Oxford: Blackwell Scientific Publications, 1975.