During top-down processing, higher cognitive processes modulate lower sensory processing. The present experiment tested the effects of directed attention on trigeminal reflex blinks in humans (n = 8). In separate sessions, participants either attended to blink-eliciting stimuli or were given no attentional instructions during stimulation of the supraorbital branch of the trigeminal nerve. Attention to blink-eliciting stimuli significantly increased reflex blink amplitude and duration and shortened blink latency compared with the no attention condition. These results suggested that higher processes such as attention can modify the trigeminal blink reflex circuit.
ArntzA.DressenL.MerckelbachH. (1991) Attention, not anxiety, influences pain. Behavior Research and Therapy29: 41–50.
2.
BassoM. A.PowersA. S.EvingerC. (1996) An explanation for reflex blink hyperexcitability in Parkinson’s disease. I. Superior colliculus. The Journal of Neuroscience16: 7308–7317.
3.
BradleyM. M.CodispotiM.LangP. J. (2006) A multi-process account of startle modulation during affective perception. Psychophysiology43: 486–497.
4.
CorbettaM.ShulmanG. L. (2002) Control of goal-directed and stimulus-driven attention in the brain. Nature Reviews Neuroscience3: 201–215.
5.
DauvergneC.EvingerC. (2007) Experiential modification of the trigeminal reflex blink circuit. The Journal of Neuroscience27: 10414–10422.
6.
EvingerC.SibonyP. A.ManningK. A.FieroR. A. (1988) A pharmacological distinction between the long and short latency pathways of the human blink reflex revealed with tobacco. Experimental Brain Research73: 477–480.
7.
FrankenteinU. N.RichterW.McIntyreM. C.RemyR. (2001) Distraction modulates anterior cingulate gyrus activations during the cold pressor test. NeuroImage14: 827–836.
8.
HackleyS. A.GrahamF. K. (1984) Early selective attention effects on cutanenous and acoustic blink reflexes. Physiological Psychology11: 235–242.
9.
KenemansJ. L.KahkonenS. (2011) How human electrophysiology informs psychopharmacology: From bottom-up driven processing to top-down control. Neuropsychopharmacology36: 26–51.
10.
KimuraJ. (1973) Disorder of interneurons in Parkinsonism. The orbicularis oculi reflex to paired stimuli. Brain118: 87–96.
11.
LangP. J.BradleyM. M.CuthbertB. N. (1990) Emotion, attention, and the startle reflex. Psychological Review97: 377–395.
12.
LiL.DuY.LiN.WuX.WuY. (2009) Top-down modulation of prepulse inhibition of the startle reflex in humans and rats. Neuroscience and Biobehavioral Reviews33: 1157–1167.
13.
LippO.NeumannD. L. (2004) Attentional blink reflex modulation in a continuous performance task is modality specific. Psychophysiology41: 417–425.
14.
MaoJ. B.EvingerC. (2001) Long-term potentiation of the human blink reflex. The Journal of Neuroscience21: 1–4.
15.
MironD.DuncanG. H.BushnellM. C. (1989) Effects of attention on the intensity and unpleasantness of thermal pain. Pain39: 345–352.
16.
PelligriniJ. J.HornA. K. E.EvingerC. (1995) The trigeminally evoked blink reflex: I. Neuronal circuits. Experimental Brain Research107: 166–180.
17.
PessoaL.KastnerS.UngerleiderL. G. (2003) Neuroimaging studies of attention: From modulation of sensory processing to top-down control. The Journal of Neuroscience23: 3990–3998.
18.
PowersA. S.SchicatanoE. S.BassoM. A.EvingerC. (1997) To blink or not to blink: Inhibition and facilitation of reflex blinks. Experimental Brain Research113: 283–290.
19.
SchicatanoE. J. (2005) Effects of caffeine on the trigeminal blink reflex. Perceptual and Motor Skills100: 493–496.
20.
SchicatanoE. J.BlumenthalT. D. (1998) The effects of caffeine and directed attention on acoustic startle habituation. Pharmacology, Biochemistry and Behavior59: 145–150.
21.
ShahaniB. (1970) The human blink reflex. Neurology, Neurosurgery & Psychiatry33: 792–800.
