A pilot study was carried out to investigate the relationship between exposure to lead and attention in children. The participants were 43 boys, 8 to 12 years of age, attending special schools for children with educational and/or learning problems (so called LOM schools). Children with probable causes of attentional or memory problems other than lead contamination were excluded from the study. Various aspects of attention were measured using neuropsychological tests. As an assessment of body lead burden, lead concentration in the boys' hair was measured by means of the Synchrotron Radiation-Induced X-ray Fluorescence technique (SXRF). Information was collected about variables that possibly could influence attention and/or body lead burden (confounding factors). A multiple regression analysis was used to determine the contribution of lead to variance in performance, after correction for confounding factors. The results showed that children with relatively high concentrations of lead in their hair reacted significantly slower in a simple reaction-time task than did children with relatively low concentrations of lead in their hair. In addition, the former were significantly less flexible in changing their focus of attention, even after correction for the influence of their delayed reaction time.
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References
1.
Baddeley, A. D. (1986). Working memory. Oxford: Clarendon Press.
2.
Baker, E. L., & Letz, R. E. (1986). Neuro-behavioral testing in monitoring hazardous workplace exposure. Journal of Occupational Medicine, 28, 987–;990.
3.
Bakker, D. J., van der Vlugt, H., & Claushuis, M. (1978). The reliability of dichotic similarity in normal children. Neuropsychologia, 16, 753–;758.
4.
Beery, K., & Buktenica, N. A. (1967). Developmental test of visual—;motor integration. Chicago: Fott, Iet.
5.
Berndsen-Peeters, K., & van der Vlugt, H. (1986). Development and application of a screening battery for the detection of hyperactive and learning-disabled children [Summary]. Journal of Experimental and Clinical Neuropsychology, 8, 122.
6.
Brand, E. F. J. M., Das-Smaal, E. A., & de Jong, P. F. (1992). Attentional and learning problems: Identification of subgroups by cluster analysis. Unpublished manuscript.
7.
Brouwer, W. H. (1985). Limitations of attention after closed head injury. Unpublished doctoral dissertation, State University Groningen, Groningen, the Netherlands.
8.
David, O. J., Hoffman, S. P., Clark, J., Grad, G., & Sverd, J. (1983). The relationship of hyperactivity to moderately elevated lead levels. Archives of Environmental Health, 38, 341–;346.
9.
de Jong, P. F. (1991). Het meten van aandacht [The assessment of attention]. Unpublished doctoral dissertation, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
10.
de Jong, P. F., & Das-Smaal, E. A. (1992). Factor structure of standard attention tests for children: A distinction between perceptual speed and working memory. Unpublished manuscript.
11.
Derix, M. M. A. (1991). Neuropsychological differentiation of dementia. Unpublished doctoral dissertation, Universiteit van Amsterdam, Amsterdam, the Netherlands.
12.
de Sonneville, L. M. J. (1988). Information processing and neonatal neurological optimality. Amsterdam: Free University Press.
13.
Emmen, H. H., Hoogendijk, E. M. G., Hooisma, J., Orlebeke, J. F., & Uijtdehaage, S. H. J. (1988). Adaptation of two standardized international test batteries for use in the Netherlands for detection of exposure to neurotoxic compounds (Tech. Rep. MBL, TNO). Rijswijk, the Netherlands.
14.
Fergusson, D. M., Fergusson, J. E., Horwood, L. J., & Kinzett, N. G. (1988). A longitudinal study of dentine lead level, intelligence, school performance and behaviour: Part II. Dentine lead and cognitive ability. Journal of Child Psychology and Psychiatry, 29, 793–;809.
15.
Grant, L. D., & Davis, J. M. (1989). Effects of low-level lead exposure on paediatric neurobehavioural development: Current findings and future directions. In M. A. Smith, L. D. Grant, & A. I. Sors (Eds.), Lead exposure and child development: An international assessment (pp. 49–;115). Dordrecht, Holland: Kluwer.
16.
Hammes, J. G. W. (1978). De Stroop kleurwoord test. Lisse: Swets & Zeitlinger.
17.
Hunter, G., Urbanowicz, M. A., Yule, W., & Lansdown, R. (1985). Automated testing of reaction time and its association with lead in children. Gut. Archives of Occupational and Environmental Health, 57, 27–;34.
18.
Langevelde, F.van, Tros, G. H. J., & Vis, R. D. (1989). The assessment of the body-burden of lead by means of the analysis of human hair using Synchrotron radiation induced x-ray fluorescence and Micro-Pixe. Journal of Trace and Microprobe Techniques, 7, 247–;262.
19.
Lansdown, R. (1986). Lead, intelligence, attainment and behavior. In R. Lansdown & W. Yule (Eds.), The lead debate: The environment, toxicology and child health (pp. 235–;270). London: Croom Helm.
20.
Lezak, M. D. (1983). Neuropsychological assessment. Oxford: Oxford University Press.
21.
Moon, Ch., Marlowe, M., Stellern, J., & Errera, J. (1985). Main and interaction effects of metallic pollutants on cognitive functioning. Journal of Learning Disabilities, 18, 217–;221.
22.
Needleman, H. L., & Gatsonis, C. A. (1990). Low-level lead exposure and the IQ of children. Journal of the American Medical Association, 263, 673–;678.
23.
Needleman, H., Gunnoe, C., Leviton, A., Reed, R., Peresie, H., Maher, C., & Barrett, P. (1979). Deficits in psychologic and classroom performance on children with elevated dentine lead levels. New England Journal of Medicine, 300, 689–;695.
24.
Quai, H. C., Routh, D. K., & Shapiro, S. K. (1987). Psychopathology of childhood from description to validation. Annual Review of Psychology, 38, 491–;532.
25.
Reitan, R. M., & Davison, L. A. (1974). Clinical neuropsychology: Current status and applications. Washington, DC: Winston & Sons.
26.
Rice, D. C. (1984). Behavioral deficit (delayed matching to sample) in monkeys exposed from birth to low levels of lead. Toxicology and Applied Pharmacology, 75, 337–;345.
27.
Rice, D. C. (1985). Behavioral toxicity in monkeys exposed to low levels of lead from birth. Toxicologist, 5, 23.
28.
Ross, D. M., & Ross, S. A. (1982). Hyperactivity: Current issues, research and theory. New York: Wiley.
29.
Rourke, B. P., Bakker, D. J., Fisk, J. L., & Strang, J. D. (1983). Child neuropsychology: An introduction to theory, research and clinical practice. New York: Guilford.
30.
Rourke, B. P., & Petrauskas, R. J. (1977). Underlining test-Revised. Windsor, Ontario: Author.
31.
Rutter, M. (1983). Low level lead exposure: Sources, effects and implications. In M. Rutter & R.E. Jones (Eds.), Lead versus health (pp. 296–;333). Chichester, England: Wiley.
32.
Shallice, T. (1988). From neuropsychology to mental structure. Cambridge: Cambridge University Press.
33.
Silva, P. A., Hughes, P., Williams, S., & Faed, J. M. (1988). Blood lead, intelligence, reading attainment, and behaviour in eleven year old children in Dunedin, New Zealand. Journal of Child Psychology and Psychiatry, 29, 43–;52.
34.
Spreen, O., & Strauss, E. (1991). A compendium of neuropsychological tests: Administration, norms and commentary. New York: Oxford University Press.
35.
Stuss, D. T., & Benson, D. F. (1986). The frontal lobes. New York: Raven.
36.
van den Bos, K. P., Eldik, M. C. M.van, Loykens E. H. M., & Ravestein, H. A. F. (1988). De cognitieve ontwikkeling van lom-schoolkinderen: Is er stagnatieTijdschrift voor Orthopedagogiek, 27, 127–;142.
37.
Wechsler, D. (1974). Wechsler intelligence scale for children-Revised. San Antonio, TX: Psychological Corp.
38.
Yule, W. (1986). Methodological and statistical issues. In R. Landsdown & W. Yule (Eds.), The lead debate: The environment, toxicology and child health (pp. 193–;216). London: Croom Helm.
39.
Yule, W., Urbanowicz, M., Lansdown, R., & Millar, I. B. (1984). Teacher's ratings of children's behaviour in relation to blood lead levels. British Journal of Developmental Psychology, 2, 295–;305.
