Different motives for cannabis use have been linked to varying consumption patterns and consequences, though findings remain inconsistent. This study examined how these motives relate to cannabis-related outcomes and tested whether Protective Behavioral Strategies (PBS) and sex moderate these associations, and whether the moderating role of PBS differs by sex. Participants were 462 young adults who reported past-month cannabis use (Mage = 20.98; 61.3% male) and completed two surveys separated by three months. Regression analyses indicated that stronger coping motives were associated with more frequent use. Moderation analysis showed that the associations of social and expansion motives with cannabis quantity was weaker at higher PBS levels. Among males, the positive associations between expansion motives and quantity, and between conformity motives and cannabis-related consequences were weaker at higher levels of PBS. These findings highlight the moderating role of PBS and suggest enhancing PBS may benefit interventions aiming to reduce cannabis-related outcomes.
BlevinsC. E.BanesK. E.StephensR. S.WalkerD. D.RoffmanR. A. (2016). Change in motives among frequent cannabis-using adolescents: Predicting treatment outcomes. Drug and Alcohol Dependence, 167, 175–181. https://doi.org/10.1016/j.drugalcdep.2016.08.018
2.
BonarE. E.GoldstickJ. E.CollinsR. L.CranfordJ. A.CunninghamR. M.ChermackS. T.BlowF. C.WaltonM. A. (2017). Daily associations between cannabis motives and consumption in emerging adults. Drug and Alcohol Dependence, 178, 136–142. https://doi.org/10.1016/j.drugalcdep.2017.05.006
3.
BravoA. J.AnthenienA. M.PrinceM. A.PearsonM. R.Marijuana Outcomes Study Team. (2017). Marijuana protective behavioral strategies as a moderator of the effects of risk/protective factors on marijuana-related outcomes. Addictive Behaviors, 69, 14–21. https://doi.org/10.1016/j.addbeh.2017.01.007
4.
BravoA. J.PearsonM. R.PilattiA.MezquitaL.Cross‐Cultural Addictions Study Team. (2019). Negative marijuana-related consequences among college students in five countries: Measurement invariance of the brief marijuana consequences questionnaire. Addiction, 114(10), 1854–1865. https://doi.org/10.1111/add.14646
5.
BravoA. J.WeinsteinA. P.PearsonM. R.Protective Strategies Study Team. (2019). The relationship between risk factors and alcohol and marijuana use outcomes among concurrent users: A comprehensive examination of protective behavioral strategies. Journal of Studies on Alcohol and Drugs, 80(1), 102–108. https://doi.org/10.15288/jsad.2019.80.102
6.
BresinK.MekawiY. (2019). Do marijuana use motives matter? Meta-analytic associations with marijuana use frequency and problems. Addictive Behaviors, 99, 106102. https://doi.org/10.1016/j.addbeh.2019.106102
7.
BucknerJ. D.JeffriesE. R.TerleckiM. A.EckerA. H. (2016). Distress tolerance among students referred for treatment following violation of campus cannabis use policy: Relations to use, problems, and motivation. Behavior Modification, 40(5), 663–677. https://doi.org/10.1177/0145445515610315
8.
BucknerJ. D.ZvolenskyM. J.CrosbyR. D.WonderlichS. A.EckerA. H.RichterA. (2015). Antecedents and consequences of cannabis use among racially diverse cannabis users: An analysis from ecological momentary assessment. Drug and Alcohol Dependence, 147, 20–25. https://doi.org/10.1016/j.drugalcdep.2014.12.022
9.
BucknerJ. D.ZvolenskyM. J.EckerA. H. (2013). Cannabis use during a voluntary quit attempt: An analysis from ecological momentary assessment. Drug and Alcohol Dependence, 132(3), 610–616. https://doi.org/10.1016/j.drugalcdep.2013.04.013
10.
BucknerJ. D.ZvolenskyM. J.SchmidtN. B. (2012). Cannabis-related impairment and social anxiety: The roles of gender and cannabis use motives. Addictive Behaviors, 37(11), 1294–1297. https://doi.org/10.1016/j.addbeh.2012.06.013
11.
CialdiniR. B.RenoR. R.KallgrenC. A. (1990). A focus theory of normative conduct: Recycling the concept of norms to reduce littering in public places. Journal of Personality and Social Psychology, 58(6), 1015–1026. https://doi.org/10.1037/0022-3514.58.6.1015
12.
ConnorJ. P.StjepanovićD.Le FollB.HochE.BudneyA. J.HallW. D. (2021). Cannabis use and cannabis use disorder. Nature Reviews Disease Primers, 7(1), 16. https://doi.org/10.1038/s41572-021-00247-4
13.
CooperM. L. (1994). Motivations for alcohol use among adolescents: Development and validation of a four-factor model. Psychological Assessment, 6(2), 117–128. https://doi.org/10.1037/1040-3590.6.2.117
14.
CooperM. L.FroneM. R.RussellM.MudarP. (1995). Drinking to regulate positive and negative emotions: A motivational model of alcohol use. Journal of Personality and Social Psychology, 69(5), 990–1005. https://doi.org/10.1037//0022-3514.69.5.990
15.
CooperM. L.KuntscheE.LevittA.BarberL. L.WolfS. (2016). Motivational models of substance use: A review of theory and research on motives for using alcohol, marijuana, and tobacco. Journal of Studies on Alcohol and Drugs, 77(5), 695–710. https://doi.org/10.1093/oxfordhb/9780199381678.013.017
16.
DillmanD. A.SmythJ. D.ChristianL. M. (2014). Internet, phone, mail, and mixed-mode surveys: The tailored design method. John Wiley & Sons.
17.
EspinosaA.RuglassL. M.ConwayF. N.JacksonK. M.WhiteH. R. (2023). Motives, frequency, and consequences of cannabis use among college students. Journal of Drug Issues, 53(1), 61–78. https://doi.org/10.1177/00220426221093608
FairchildA. J.MacKinnonD. P. (2009). A general model for testing mediation and moderation effects. Prevention Science: The Official Journal of the Society for Prevention Research, 10(2), 87–99. https://doi.org/10.1007/s11121-008-0109-6
22.
FetterlingT.ParnesJ.PrinceM. A.ConnerB. T.GeorgeM. W.ShillingtonA. M.RiggsN. R. (2021). Moderated mediation of the eCHECKUP TO GO college student cannabis use intervention. Substance Use & Misuse, 56(10), 1508–1515. https://doi.org/10.1080/10826084.2021.1937225
23.
FlemingC. B.Walukevich-DienstK.CalhounB. H.LeeC. M. (2023). A longitudinal analysis of monthly changes in substance use in relation to negative consequences from alcohol and cannabis use in a community sample of young adults. Journal of Studies on Alcohol and Drugs, 84(6), 913–920. https://doi.org/10.15288/jsad.22-00431
24.
GenrichG.ZellerC.ZnojH. J. (2021). Interactions of protective behavioral strategies and cannabis use motives: An online survey among past-month users. PLoS One, 16(3), Article e0247387. https://doi.org/10.1371/journal.pone.0247387
25.
González-PonceB. M.Carmona-MárquezJ.Díaz-BataneroC.VeraB. D. V.PilattiA.Fernández-CalderónF. (2022). A longitudinal study among young adults into the predictive effect of perceived efficacy of behavioural strategies and the moderating role of drinking motives on use of protective behavioural strategies. Drug and Alcohol Review, 41(4), 795–802. https://doi.org/10.1111/dar.13422
GrigsbyT. J.LopezA.AlbersL.RogersC. J.ForsterM. (2023). A scoping review of risk and protective factors for negative cannabis use consequences. Substance Abuse: Research and Treatment, 17, 11782218231166622. https://doi.org/10.1177/11782218231166622
28.
HayesA. F. (2017). Introduction to mediation, moderation, and conditional process analysis: A regression-based approach. Guilford Publications.
29.
HemsingN.GreavesL. (2020). Gender norms, roles and relations and cannabis-use patterns: A scoping review. International Journal of Environmental Research and Public Health, 17(3), 947. https://doi.org/10.3390/ijerph17030947
30.
JongenelisM. I.PettigrewS.PrattI. S.ChikritzhsT.SlevinT.LiangW. (2016). Predictors and outcomes of drinkers’ use of protective behavioral strategies. Psychology of Addictive Behaviors, 30(6), 639–647. https://doi.org/10.1037/adb0000194
31.
LansfordJ. E.GoulterN.GodwinJ.McMahonR. J.DodgeK. A.CrowleyM.PettitG. S.BatesJ. E.LochmanJ. E. (2023). Predictors of problematic adult alcohol, cannabis, and other substance use: A longitudinal study of two samples. Development and Psychopathology, 35(4), 2028–2043. https://doi.org/10.1017/S0954579422000670
32.
MemedovichK. A.DowsettL. E.SpackmanE.NoseworthyT.ClementF. (2018). The adverse health effects and harms related to marijuana use: An overview review. CMAJ Open, 6(3), E339–E346. https://doi.org/10.9778/cmajo.20180023
33.
MezquitaL.Ruiz-ValeroL.Martínez-GómezN.IbáñezM. I.OrtetG. (2019). Development and validation of the marijuana motives measure short form. Desarrollo y validación de la versión breve del cuestionario de motivos de consumo de marihuana (MMM SF). Adicciones, 31(2), 106–116. https://doi.org/10.20882/adicciones.979
34.
MorrisP. E.BucknerJ. D. (2023). Cannabis-related problems and social anxiety: The roles of sex and cannabis use motives updated. Addictive Behaviors, 137, 107528. https://doi.org/10.1016/j.addbeh.2022.107528
Parrado-GonzálezA.Fernández-CalderónF.CarmonaJ.del Valle VeraB. (2025). The role of habit and past behavior in cannabis use: An extended theory of planned behavior model[preprint]. OSF Preprints. https://doi.org/10.31219/osf.io/ckq9j_v1
37.
PatrickM. E.PangY. C.Terry-McElrathY. M.ArterberryB. J. (2024). Historical trends in cannabis use among U.S. adults aged 19-55, 2013-2021. Journal of Studies on Alcohol and Drugs, 85(4), 447–486. https://doi.org/10.15288/jsad.23-00169
38.
PearsonM. R.BravoA. J.ConnerB. T.ParnesJ. E. (2020). A day in the life: A daily diary examination of marijuana motives and protective behavioral strategies among college student marijuana users. Journal of Drug Issues, 50(2), 142–156. https://doi.org/10.1177/0022042619890837
39.
PearsonM. R.Marijuana Outcomes Study Team. (n.d.). Marijuana Use Grid: A brief, comprehensive measure of marijuana use. Unpublished manuscript.
40.
PedersenE. R.HuangW.DvorakR. D.PrinceM. A.HummerJ. F.The Marijuana Outcomes Study Team. (2017). The protective behavioral strategies for marijuana scale: Further examination using item response theory. Psychology of Addictive Behaviors, 31(5), 548–559. https://doi.org/10.1037/adb0000271
41.
PetersonR.KramerM. P.PintoD.De LeonA. N.LearyA. V.MarinA. A.CoraJ. L.DvorakR. D. (2021). A comprehensive review of measures of protective behavioral strategies across various risk factors and associated PBS-Related interventions. Experimental and Clinical Psychopharmacology, 29(3), 236–250. https://doi.org/10.1037/pha0000498
42.
RichardsD. K.GreńJ. D.PearsonM. R.Addictions Research TeamProtective Strategies Study Team. (2023). Profiles of alcohol and cannabis protective behavioral strategies use across two large, multi-site college student samples of concurrent alcohol and cannabis users. Addictive Behaviors, 146, 107789. https://doi.org/10.1016/j.addbeh.2023.107789
43.
RichardsD. K.SchwebelF. J.BravoA. J.PearsonM. R.Cross-Cultural Addictions Study Team. (2021). A comparison of cannabis protective behavioral strategies use across cultures and sex. Addictive Behaviors, 120, 106966. https://doi.org/10.1016/j.addbeh.2021.106966
44.
RichardsD. K.SchwebelF. J.PearsonM. R.Study TeamP. S. (2021). A test of interaction effects between cannabis protective behavioral strategies and antecedents of cannabis-related consequences. Journal of Psychoactive Drugs, 54(1), 61–69. https://doi.org/10.1080/02791072.2021.1909188
45.
RochatL.RothenS.EdelY.PenzenstadlerL.LecomteT.PotvinS.Dan GlauserE.EtterJ. F.KhazaalY. (2024). Measurement invariance of the marijuana motives measure among men and women using stop cannabis app. Addictive Behaviors, 148, 107866. https://doi.org/10.1016/j.addbeh.2023.107866
46.
Sánchez-GarcíaM.Carmona-MárquezJ.BravoA. J.Fernández-CalderónF. (2024). Spanish adaptation and psychometric properties of the protective behavioral strategies for marijuana scale: The protective behavioral strategies for cannabis scale (S-PBSC). International Journal of Mental Health and Addiction, 23(5), 3648–3671. https://doi.org/10.1007/s11469-024-01311-2
47.
ShiffmanS. (2009). Ecological Momentary Assessment (EMA) in studies of substance use. Psychological Assessment, 21(4), 486–497. https://doi.org/10.1037/a0017074
48.
ShrierL. A.SchererE. B. (2014). It depends on when you ask: Motives for using marijuana assessed before versus after a marijuana use event. Addictive Behaviors, 39(12), 1759–1765. https://doi.org/10.1016/j.addbeh.2014.07.018
49.
SimonsJ. S.CorreiaC. J.CareyK. B.BorsariB. E. (1998). Validating a five-factor marijuana motives measure: Relations with use, problems, and alcohol motives. Journal of Counseling Psychology, 45(3), 265–273. https://doi.org/10.1037/0022-0167.45.3.265
50.
SimonsJ. S.DvorakR. D.MerrillJ. E.ReadJ. P. (2012). Dimensions and severity of marijuana consequences: Development and validation of the Marijuana Consequences Questionnaire (MACQ). Addictive Behaviors, 37(5), 613–621. https://doi.org/10.1016/j.addbeh.2012.01.008
51.
ThompsonS. K.CollinsL. M. (2002). Adaptive sampling in research on risk-related behaviors. Drug and Alcohol Dependence, 68(Suppl 1), S57–S67. https://doi.org/10.1016/s0376-8716(02)00215-6
52.
TurnerS.MotaN.BoltonJ.SareenJ. (2018). Self-medication with alcohol or drugs for mood and anxiety disorders: A narrative review of the epidemiological literature. Depression and Anxiety, 35(9), 851–860. https://doi.org/10.1002/da.22771
WallisD.CoatsworthJ. D.MennisJ.RiggsN. R.ZaharakisN.RussellM. A.BrownA. R.RayburnS.RadfordA.HaleC.MasonM. J. (2022). Predicting self-medication with cannabis in young adults with hazardous cannabis use. International Journal of Environmental Research and Public Health, 19(3), 1850. https://doi.org/10.3390/ijerph19031850
