Granular cell tumor (GCT) of the lung is a rare tumor, constituting less than 10% of all GCTs. It is a multicentric tumor and infiltrates into adjoining tissue, but malignant GCT of the lung has not been reported. Diagnosis is usually obtained with bronchoscopic biopsy. Treatment options include bronchoscopic extirpation, laser therapy, and sleeve resection. We present a case of GCT co-existing with adenocarcinoma of the lung and review the literature.
AbrikossoffA.Uber Myome, ausgehend von der quergestreiften willkurlichen Muskulatur. Virchows Arch Pathol Anat Physiol Klin Med1926;260:215–233.
2.
KramerR.Myoblastoma of the bronchus. Ann Otol Rhinol Laryngol1939;48:1083–1086.
3.
LackEE, WorshamGF, CallihanMD, CrawfordBE, KlappenbachS, RowdenG, ChunB.Granular cell tumor: a clinicopathologic study of 110 patients. J Surg Onc1980;13(4):301–316.
4.
OparahSS, SubramanianVA. Granular cell myoblastoma of the bronchus: report of 2 cases and review of literature. Ann Thorac Surg1976;22(2):199–202.
5.
RobinsonJM, KnollR, HenryDA. Intrathoracic granular cell myoblastoma. South Med J1988;81(11):1453–1457.
6.
DeaversM, GuineeD, KossMN, TravisWD. Granular cell tumor of the lung: clinicopathologic study of 20 cases. Am J Surg Pathol1995;19(6):627–635.
7.
KhansurT, BalducciL, TavassoliM.Granular cell tumor: clinical spectrum of the benign and malignant entity. Cancer1987;60(2):220–222.
8.
ParkSH, KimTJ, ChiJG. Congenital granular cell tumor with systemic involvement: immunohistochemical and ultrastructural study. Arch Pathol Lab Med1991;115(9):934–938.
9.
SchulsterPL, KhanFA, AzuetaV.Asymptomatic pulmonary granular cell tumor presenting as a coin lesion. Chest1975;68(2):256–258.
10.
OrdonezNG. Granular cell tumor: a review and update. Adv Anat Pathol1999;6(4):186–203.
11.
HurwitzSS, ConlanAA, GritzmanMC, KrutLH. Coexisting granular cell myoblastoma and squamous carcinoma of the bronchus. Thorax1982;37(5):392–393.
12.
GabrielJBJr, ThomasL, MendozaCB, ChauhanPM. Granular cell tumor of the bronchus coexisting with a bronchogenic adenocarcinoma: a case report. J Surg Oncol1983;24(2):103–106.
13.
TamayoJL, RojasMC. Granular cell myoblastoma (granular cell schwannoma) of the right upper bronchus coexisting with a bronchogenic carcinoma: report of the first case in the literature. J Thorac Cardiovasc Surg1971;62(2):268–270.
14.
DabouisG, NomballaisMF, MauryB, PeltierP, MorineauJF, CorrollerJ.[Endobronchial Abrikosov's tumor: two new cases associated to malignant tumors.]Poumon Coeur1979;35(4):211–216. article in French
15.
LiebmanJ, LinthicumCM. Granular cell myoblastoma (schwannoma) of the carina in a patient with sarcoidosis. South Med J1976;69(12):1613–1615.
16.
GantiS, MarinoW.Granular cell myoblastoma in an HIV positive patient. NY State J Med1991;91(6):265–266.
17.
GlantMD, WallRW, RansburgR.Endobronchial granular cell tumor: cytology of a new case and review of literature. Acta Cytol1979;23(6):477–482.
KrouseTB, MobiniJ.Multifocal granular cell myoblastoma: report of a case involving trachea, stomach, and anterior abdominal wall. Arch Pathol1973;96(2):95–99.
McLainWC3rd, OlsenGN, WooldridgeD, AlmondCH, BoykinAB. Endotracheal granular cell myoblastoma: a failure of laser therapy. Chest1984;86(1):136–137.
22.
DanielTM, SmithRH, FaunceHF, SylvestVM. Transbronchoscopic versus surgical resection of tracheobronchial granular cell myoblastomas: suggested approach based on follow-up of all treated cases. J Thorac Cardiovasc Surg1980;80(6):898–903.
23.
De ClercqD, Van der StraetenM, RoelsH.Granular cell myoblastoma of the bronchus. Eur J Respir Dis1983;64(1):72–76.
