Glucose concentrations of 248 newborns at 1 and 3 hours of age were determined at the bedside by means of the Accu-Chek III Reflectance® meter and in the laboratory by means of the Vitros 750® analyzer. Hypoglycemia being defined as a glucose concentration less than 40 mg/dL, the reflectance meter had a sensitivity of 0.757 and a specificity of 0.876 at 1 hour and 0.975 at 3 hours. The imprecision of the reflectance meter at 1 hour eliminated it as a routine testing method.
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References
1.
1. Srinivasan G, Pildes RS, Cattamanchi G, et al. Plasma glucose values in neonates: a new look. J Pediatr.1986; 109:114-117.
2.
2. Cole P. Hypoglycemia in normal neonates appropriate for gestational age.J Perinat. 1994;14:118-120.
3.
3. Cornblath M, Schwartz R. Disorders of Carbohydrate Metabolism in InfancyPhiladelphia: WB Saunders; 1976:187-195.
4.
4. Cornblath M, Schwartz R. Hypoglycemia in the neonate. J Pediatr Endocrinol. 1993;6:113-127.
5.
5. Halamek L, Stevenson D. Neonatal hypoglycemia, Part II: Pathophysiology and therapy. Clin Pediatr. 1998; 37:11-16.
6.
6. Committee of Fetus and Newborn. Routine evaluation of blood pressure, hematocrit and glucose in newborns. Pediatrics. 1993;92:474-476.
7.
7. Conrad P, Sparks J, Osberg I, et al. Clinical application of a new glucose analyzer in the neonatal intensive care unit: comparison with other methods. J Pediatr.1989;114:281-287.
8.
8. Perkins S, Doelle H, Escares E, et al. Laboratory and clinical evaluation of two glucose meters for the neonatal intensive care unit. Clin Biochem. 1998;31:67-71.
9.
9. Nicols J, Howard C, Loman K, et al. Laboratory and bedside evaluation of portable glucose meters. Am J Clin Pathol. 1995;103:244-251.
10.
10. Cornbleet PJ, Gochman N. Incorrect least-squares regression coefficients in method comparison analysis. Clin Chem. 1979;25:432-438.
11.
11. Metz C. Basic Principles ofROCAnalysis, Seminars in Nuclear Medicine. 1978; 8:283-298.
12.
12. Sexson W. Incidence of neonatal hypoglycemia: a matter of definition. J Pediatr.1984;105:149-150.