This report describes a 3-week-old infant with paregoric intoxication and pul monary edema. The pulmonary edema associated with opiod use is treatable even though the precise mechanism of its formation remains undefined. The report emphasizes that the medical rationale involved in the use of paregoric is unclear. The use of this preparation in pediatric patients should be abandoned in view of such serious complications.
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References
1.
Ulshen MHDiarrhea. In: Hoekelman RA, ed. Principles of pediatrics. New York: McGraw-Hill, 1978: 722-34.
2.
Garrett JM, Sauer WG, Moertel CGColonic motility in ulcerative colitis after opiate administration. Gastroenterology1967;53:93-100.
3.
Jaffe JHNarcotic analgesics. In: Goodman LS, Gilman AF, eds. The Pharmacological Basis of Therapeutics. New York: MacMillan , 1970:237-75.
4.
British Pharmaceutical Codex.Opium. London: The Pharmaceutical Press, 1968:555.