A 3-year-old boy who presented with signs of virilization had a Leydig cell tumor of the left testis that could not be detected by physical examination or by high resolution ultrasonography. His very small tumor was demonstrated by magnetic resonance imaging. The implications of adding this sensitive method of imaging to the evaluation of prepubertal virilization of presumed testicular etiology are discussed.
Get full access to this article
View all access options for this article.
References
1.
Urban M., Lee P., Plotnick L., et al. The diagnosis of Leydig cell tumors in childhood. Am J Dis Child1978; 132:494-7.
2.
Wilson B., Netzloff M.Primary testicular abnormalities causing precocious puberty. Ann Clin Lab Sci1983; 13:315-20.
3.
Rosenthal S. , Grumbach M., Kaplan S.Gonadotropin-independent familial sexual precocity with premature Leydig and germinal cell maturation. JCEM1983; 57:571-9.
