ORAL ANTIBIOTIC TREATMENT of acute staphylococcal osteomyelitis in toddler and school-age children has proven a cost-effective and efficacious alternative to intravenous therapy. 1,2 Oral antibiotic regimens, however, have not been carefully studied in neonatal osteomyelitis. We recently treated an infant with oral antibiotics for multifocal group B streptococcal (GBS) osteomyelitis and suppurative arthritis and report our experience.
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