Two cases of nonbacterial endocardial thrombi (NBET) on the atrial surface of the tricuspid valve in the full-term infant are presented. The pathophysiology and the events peculiar to the full-term infant that suggest susceptibility to this rare pathological phenomenon are reviewed. The difficulties in diagnosis and treatment are discussed.
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References
1.
Favara BE, Franciosi RA, Butterfield LJDisseminated intravascular and cardiac thrombosis of the neonate. Am J Dis Child Feb 1984;127:197-204.
Liwnicz BH, Lepow H.Nonbacterial thrombotic endocarditis in premature child. NY State J Med1976;6:912-6.
4.
Morrow WR, Haas JE, Benjamin DRNonbacterial endocardial thrombosis in neonates: relationship to persistent fetal circulation. J Pediatr1982;100:117-22.
5.
Chessells JM , Wigglesworth JSCoagulation studies in severe birth asphyxia. Archives Disease in Childhood1971 ;46:253-6.
6.
Levin DL, Weinberg AG, Perkin RMPulmonary microthrombi syndrome in newborn infants with unresponsive persistent pulmonary hypertension. J Pediatr1983;101:299-303.
7.
Mahony L., Snider AR, Silverman NHEchocardiographic diagnosis of intracardiac thrombi complicating total parenteral nutrition. J Pediatr1981 ;98: 469-71.
8.
Chessells JM , Wigglesworth JSCoagulation studies in severe birth asphyxia . Arch Dis Child1971 ;46:253-6.
9.
Hathaway WE, Rudolph, Textbook of pediatrics. 1982, pp. 1110-24.
10.
Plaut A.Acute valvular endocarditis in the newborn. Arch Pathol1935;20:582-6.
Casin S.Role of prostaglandins and thromboxanes in the control of the pulmonary circulation in the fetus and newborn. Seminars Perinato1980;4:101-7.
13.
Boyd JFDisseminated fibrin thromboembolism among stillbirths and neonatal deaths . J Path Bact1965;90: 53-6.
14.
Jeffries IP , Hersh CBPersistent fetal circulation. J Florida Med Assoc1983;70:794-7.
15.
Bucciarelli RL, Nelson RM, Egan EA, et al. Transient tricuspid insufficiency of the newborn: a form of myocardial dysfunction in stressed newborns. Pediatr1977;59:330-7.
16.
Aballi AJ, De Lamerens S.Coagulation changes in the neonatal period and in early infancy. Pediatr Clin North Am1962;9:785-817.
17.
Buchanan GRNeonatal coagulation: normal physiology and pathophysiology. Clin Haemato1978;7:85-109.
18.
Chadd MACoagulation defects in hypoxic full-term infants, Br J1971;4:515.
19.
Bancalari E. , Berlin J.Meconium aspiration and other asphyxial disorders . Clin Perinato1978;5:317-34.
20.
Dillon JC, Feigenbaum H., Konecke LL, et al. Echocardiographic manifestations of valvular vegetations. Am Heart J1973;86:698-704.
21.
Segall ML, Geotzman BW, Schick JBThrombocytopenia and pulmonary hypertension in the perinatal aspiration syndromes . J Pediatr1980;96:727-30.
22.
Melvin ET, Berger M., Lutzker LG, et al. Noninvasive methods for detection of valve vegetations in infective endocarditis. Am J Cardio1981;27:271-8.
23.
Symchych P. , Krauss A., Winchester P.Endocarditis following intracardiac placement of umbilical venous catheters in neonates. J Pediatr1977;90:287-9.
24.
Lim SP, Hakim SZ, van der Bel-Kahn JM, et al. Two-dimensional echocardiography for detection of primary right atrial thrombus in pulmonary embolism. Am Heart J1984;108:1546-7.
25.
Quinn TJ, Plehn JF, Liebson PREchocardiographic diagnosis of mobile right atrial thrombus: early recognition and treatment. Am Heart J Dec 1984;108: 1548-50.
26.
Bucciarelli RL, Jaffe R.Noninvasive evaluation of superior vena caval and right atrial thrombosis complicating central hyperalimentation. Clin Pediatr1983;22:302-3.
27.
Cameron J., Pohlner P., Stafford E., et al. Right heart thrombus: recognition, diagnosis, and management . JACC1985;5:1239-43.