Thrombocytopenia associated with Mycobacterium tuberculosis infection de veloped concurrently in a mother and son. Antiplatelet antibodies were dem onstrated in the serum of both patients. It is suggested that this and possibly other hematologic complications associated with tuberculosis are immune me diated.
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References
1.
Cameron SJTuberculosis and the btood—a special relationship?Tubercle (Edinburgh) 1974;55:55.
2.
Murray HCTransient auto-immune hemolytic anemia and pulmonary tuberculosis. N Engl J Med1978;299:488.
3.
Andre J., Schwartz R., Dameshek W.Tuberculosis and myeloscierosis with myeloid metaplasia; a report of three cases. JAMA1961;178:1169.
4.
Chai Y., Machin S.Tuberculosis and severe thrombocytopenia. Br J Clin Prac1979;33:55.
5.
von dem Borne AEG Kr, Verheught FWA , et al. A simple immunofluorescence test for the detection of platelet antibodies. Br J Haematol1978;39:195.
6.
von dem Borne AEG Kr, Helmerhorst FM, et al. Auto-immune thrombocytopenia: detection of platelet auto-antibodies with suspension immunofluorescence. Br J Haematol1980;45:319.
7.
Cimo BL, Pisciotta AVDetection of drug dependent antibodies by the 51Cr platelet lysis test. Am J Hematol1977;2:65.
8.
Kunicki TJ, Aster RHDirect quantitation of platelet associated IgG by electroimmunoassay. Blood1982;60:54.
9.
Glasser R., Walker R., Herion J.The significance of hematologic abnormalities in patients with tuberculosis . Arch Intern Med1970; 125:691.
10.
Cobur R., England J., et al. Tuberculosis and blood disorders. Br J Haematol1973;25:793.
11.
Blajchman M. , Lowry R., et al. Rifampin induced thrombocytopenia . Br J Haematol1970;3:24.
12.
Katz P., Goldstein R., Fauci A.Immunoregulation in infection caused by Mycobacterium tuberculosis; the presence of suppressor monocytes and the alteration of subpopulations of T-lymphocytes . J Infect Dis1979;140:12.
13.
Nilsson B., Sultzer B., Bullock W.Purified protein derivative of tuberculin induced immunoglobulin production in normal mouse spleen cells. J Exp Med1973 ;137:127.
