Dopamine is an effective inotropic agent in the management of circulatory collapse. Ventricular dysrhythmias are reported to occur during dopamine in fusion. The following report describes an infant with circulatory failure who experienced an episode of paroxysmal supraventricular tachycardia while receiving dopamine. Instability or immaturity of the cardiac conduction system during early infancy may contribute to the induction of an arrhythmia of supra ventricular origin.
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References
1.
Loeb HS, Winslow EB, Rahimtoola SH, Rosen KM, Gunnar RN: Acute hemodynamic effects of dopamine in patients with shock. Circulation44: 163, 1971
2.
Driscoll DJ, Gillete PC, McNamara DG: The use of dopamine in children. J Pediatr92:309, 1978
3.
Goldberg LI: Cardiovascular and renal actions of dopamine: Potential clinical applications . Pharmacol Rev24:1, 1972
4.
Shahar E., Barzilay Z., Frand M.: Verapamil in the treatment of paroxysmal supraventricular tachycardia in infants and children, J Pediatr, 98: 323, 1981
5.
Tally RC, Goldberg LI, Johnson CE, McNay JL: A hemodynamic comparison of dopamine and isoproterenol in patients with shock . Circulation39:361, 1969
6.
Reid PR, Thompson L.: The clinical use of dopamine in the treatment of shock. Johns Hopkins Med J137:276, 1975.
7.
Haddy FJ: Pathophysiology and therapy of the shock of myocardial infarction . Ann Intern Med79: 809, 1970
8.
Kun LA: Shock in myocardial infarction—medical treatment. Am J Cardiol26:578, 1970
9.
James T.: The Wolff-Parkinson-White syndrome: evolving of its pathogenesis. Prog Cardiovasc Dis12:149, 1970
10.
Tsai TH, Langer SZ, Trendelenburg V.: Effects of dopamine and alpha methyldopamine on smooth muscle and on the cardiac pacemaker. J Pharmacol Exp Ther156:310, 1967
11.
Brunjes S., Castner E., Hodgmen J.: Catecholamines metabolism in newborn infants. Clin Res12:88, 1964
12.
Loggie Jmh, Van Maanen EF: The autonomic nervous system and some aspects of the use of autonomic drugs in children. J Pediatr81:205, 1972
13.
Massing GK, Liebman J., James TN: Cardiac conduction pathways in the infant and child. Cardiovasc Clin4:27, 1972
14.
Mehta SS, Kronzon I., Laniado S.: Electrocardiographic changes in meningitis. Isr J Med Sci10: 748, 1974
15.
Silenzi M., Bernini G., Corvaglia E.: Alterazioni electrocardiografiche e compromissione miocardica in corso di sepsi meningococcica nell'infanzia. Minerva Pediatr25:1453, 1973
16.
Pediatric Cardiology. Edited by Nadas AS, Fyler DC.Philadelphia, WB Saunders, 1972, p 196
