Levamisole Treatment in Acute Hepatitis

Abstract

Fifty-six and forty patients with acute icteric hepatitis were given levamisole and placebo, respectively, for the first 3 days of a week of the disease for 2 weeks, and continued through the third and fourth weeks if their hepatitis was not resolved. Liver functions of the levamisole-treated patients became normal slightly faster than the controls'. The normalization time of trans aminases was found barely significantly shorter in the levamisole-treated group than in. the controls (p < 0.05). Additional studies with larger groups of antigenetically different types of hepatitis are warranted to determine whether treatment with levamisole might lessen the chances of developing chronic hepatitis.