Glucose intolerance preceding pulmonary disease in a child with cystic fibrosis is de scribed. After glucose intolerance was con trolled with tolbutamide, the pulmonary infec tion resolved. Early recognition and treatment of "diabetes" in children with cystic fibrosis is emphasized.
Get full access to this article
View all access options for this article.
References
1.
Rosan, R.C., Shwachman, H. and Kulczycki, L.L.: Diabetes mellitus and cystic fibrosis of the pancreas. Am. J. Dis. Child.104: 75, 1962.
2.
Handwerger, S., Roth, J., Gorden, P., di Sant'Agnese , P., Carpenter, D.F. and Peter, F.: Glucose intolerance in cystic fibrosis. N. Engl. J. Med.281: 451, 1969 .
3.
Kaiser, G., Zuppinger, K. and Joss, E.: Mucoviszidose and diabetes mellitus. Helv. Paediatr. Acta.25: 135, 1970.
4.
Shwachman, H. , Redmond, A. and Khaw, K.T.: Studies in cystic fibrosis: report of 130 patients diagnosed under three months of age over a 20-year period. Pediatrics46: 335, 1970.
5.
Milner, A.D. : Blood glucose and serum insulin levels in children with cystic fibrosis. Arch. Dis. Child.44: 351, 1969.
6.
Morgan, C.R. and Lazarow, A.: Immunoassay of insulin; two antibody systems . Diabetes12: 115, 1963.
7.
Berson, S.A. and Yalow, R.S.: Plasma insulin in health and disease. Am. J. Med.31: 847, 1961.
8.
Boshell, B.R. , Wilensky, A.S., Wayland, J. and Carr, J.H., Jr.: A new oral diagnostic test for diabetes mellitus. Metabolism12: 108, 1963.
9.
Marble, A., White, P., Bradley, R.F. and Krall, L.P.: Joslin's Diabetes Mellitus, 11th ed. Philadelphia, Lea & Febiger, 1971, p. 12.
10.
Milunsky, A. , Bray, G.A., Londono, J. and Loridan, L.: Insulin, glucose, growth hormone, and free fatty acids; determinations in patients with cystic fibrosis. Am. J. Dis. Child.121: 15, 1900.
11.
Joffe, B.I. , Bank, S., Jackson, W.P.U. and Keller, P.: Insulin reserve in patients with chronic pancreatitis. Lancet2: 890, 1968.
12.
Megyesi, C. , Samols, E. and Marks, V.: Glucose tolerance and diabetes in chronic liver disease. Lancet2: 1051, 1967.